Suggested citation: Gomes ICP, Melo HI, Melo SIA, Menezes NV, Dantas TVP, Cipolotti R. Growth and puberty in a prospective cohort of patients with sickle-cell anaemia: an assessment over ten years. J Hum Growth Dev. 2017; 7(1): 91-98 AbstractIntroduction: Hereditary haemoglobinopathies are the most common group of monogenic hereditary diseases in the world. Erythrocytes in sickle form, cellular expression of polymerization of deoxygenated HbS, cause intermittent vascular obstruction, leading to tissue ischaemia and consequent chronic damage in organs and endocrine glands.