This paper demonstrates a selective, expeditious and facile electrochemical approach for the ultrasensitive detection of atropine in complex matrices.

The adsorption of phenol on Date Seed Carbon (DSC) was investigated to assess its possible use as an adsorbent for the processing of phenolic wastewater. The influence of various factors such as initial concentration, agitation speed, amount of adsorbent and temperature on the adsorption capacity has been studied. The percentage removal of phenol was observed to increase with increase an initial concentration of phenol. The adsorption of phenol decrease with an increase in temperature indicated the exothermic nature of the reaction. The Langmuir and Freundlich equations interpret adsorption isothermal data. Kinetic data was obtained by using a pseudo-second-order equation to understand the reaction mechanism. Thermodynamic parameters such as DG, DH and DS for the adsorption process were calculated.

Herein, we report the development of a selective and highly sensitive electrochemical sensing of paeonol at carbon nanotubes modified glassy carbon electrode (GCE). Trace amount of paeonol was quantitated by employing square wave voltammetry technique for the first time based on the electrochemical oxidation of the analyte at the modified electrodes. The single walled carbon nanotubes (SWNTs) based sensor exhibited higher recognition ability of paeonol in comparison with the multi walled carbon nanotubes (MWNTs) based sensor. The linear dynamic range was found to be 100 nM – 25 μM for SWNTs modified GCE and 1–25 μM for MWNTs modified GCE. The sensitivity at SWNTs modified GCE was ∼ 3.5 times more than that at MWNTs modified GCE. The limit of detection was estimated to be 9.57 nM and 0.63 μM corresponding to SWNTs and MWNTs modified GCE respectively. The influence of experimental parameters affecting sensor response was optimized. The stability, reproducibility tests and interference effects were demonstrated to confirm the reliability of the proposed sensor. The applicability of the developed sensor was successfully assessed through convenient measurements of paeonol in biological samples and Cortex moutan which exhibits anticancer effect.

The significance of sulfasalazine (SSZ) as a therapeutic agent has garnered paramount research interest in the design and fabrication of a viable sensor for the detection of SSZ. Herein, we demonstrate a new strategy for the sensitive determination of SSZ employing single walled carbon nanotubes decorated with Fe3O4 nanoparticles sensing platform for the first time. The synthesized Fe3O4 nanoparticles and the surface morphology of the developed sensor were investigated by exerting various analytical techniques. The optimization of operational parameters was effectuated. The developed sensor exhibited pronounced electrocatalytic activity for the electro oxidation of SSZ in the dynamic detection range of 25 nM–1.5 μM manifesting noteworthy high sensitivity and phenomenal low detection limit of 18.6 μA μM−1 and 1.6 nM respectively. Apparent specificity in the presence of interferents along with remarkable stability and reproducibility were attained by the sensor. The prominence of the developed methodology was emphasized by the determination of SSZ in pharmaceutical formulations. Furthermore, the applicability of the developed electrode was established by utilizing it effectually for the first time to quantify SSZ in serum sample of patients undergoing pharmacological treatment for rheumatoid arthritis.