ObjectivesEvaluation of a new material, high-density porous polyethylene (HDPP), which is covered with fascia lata, for experimental nasal septal perforation closure.MethodsTwenty New Zealand albino rabbits were included and divided into study and control groups. A lateral incision was made from the lateral aspect of the left nares to the incisura nasomaxillaris. After exposure of the cavum nasi, the nasal mucoperichondrium was elevated bilaterally. A full-thickness 0.5×0.5-cm perforation was created over the septum nasi with a No. 11 surgical blade. A fascia lata graft was used for the study group. The HDPP was covered with fascia lata and placed under the elevated mucosa. HDPP without a fascial covering was used in the control group. Four months after the procedure, magnetic resonance imaging was performed to evaluate resorption of the material. The animals were sacrificed, and the nasal septum was completely removed. Macroscopic and histopathological examinations were performed on the nasal septum.ResultsAll rabbits had survived after the 4-month period. Macroscopically, nine of 10 (90%) perforations were closed in the fascia lata-covered HDPP group. Histopathological examination of these nine rabbits revealed that the continuity of cartilage was disturbed in the perforation areas. Granulation tissue was inverted in areas in which the cartilage continuity was disturbed. The HDPP had remained intact at the edge of the perforation. In the HDPP group, six of 10 implants were still perforated (60%) and four (40%) were closed. The fascia lata-covered HDPP implant had a significantly higher perforation closure rate than that of the HDPP implant alone (P<0.05).ConclusionIn cases of septal perforation, it is better to cover the HDPP implant with fascia lata. This covered implant can be used for the repair of nasal septal perforations. HDPP implants are easy to work with and avoid the increased operative time and morbidity associated with harvesting autografts.
Objective. To investigate the compression of the vestibulocochlear nerve in the etiology of the tinnitus in the normal hearing ears with temporal bone computed tomography scans. Methods. A prospective nonrandomized study of 30 bilateral tinnitus and 30 normal hearing patients enrolled in this study. Results. A total of 60 patients (ages ranged from 16 to 87) were included. The tinnitus group comprised 11 males and 19 females (mean age 49,50 ± 12,008) and the control group comprised 6 males and 24 females (mean age 39,47 ± 12,544). Regarding the right and left internal acoustic canals measurements (inlet, midcanal, and outlet canal lengths), there were no significant differences between the measurements of the control and tinnitus groups (P > 0.005). There was no narrowness in the internal acoustic canal of the tinnitus group compared with the control group. High-frequency audiometric measurements of the right and left ears tinnitus group at 8000, 9000, 10000, 11200, 12500, 14000, 16000, and 18000 Hz frequencies were significantly lower than the control group thresholds (P < 0.05). There was high-frequency hearing loss in the tinnitus group. Conclusion. There were no anatomical differences in the etiology of tinnitus rather than physiological degeneration in the nerves.
Objective:The relationship between the cribriform plate and the uncinate process may be elaborated with the help of the Keros classification. The observations were analysed using high-resolution computed tomography (HRCT). Additionally, the relationship between the superior attachment of the uncinate process, the existence of concha bullosa, and the different types of ethmoid roofs were examined. Methods: Five-hundred and sixteen subjects complaining of sinonasal disorders between 2015 and 2016 were enrolled retrospectively at the Okmeydani Training and Research Hospital, Department of Otolaryngology. HRCT scans of 1-mm sections were obtained. Keros classification was used for the measurement of the depth of the olfactory fossa as follows: Keros I: 1-3 mm, Keros II: 3-7 mm, and Keros III: 7-16 mm. Results: Fifty-one point nine percentage of cases were of Keros type II, 27.7% of type III, and 20.3% of type I. In 82.4% of the reported cases, the uncinate process was attached to the lamina papyraceae, in 11% of the cases it was attached to the middle nasal turbinate, and in 6.4% cases to the skull base. A concha bullosa was observed in the right nasal cavity in 13.8% of the cases, in the left nasal cavity in 11% of the cases, and bilaterally in 16.3% of the cases. Variances observed in the Keros types were not statistically significant with respect to sex (p>0.05). Concha bullosa was significantly more frequently seen in females (53.1%) relative to males (p=0.001). Conclusion: Endoscopic sinus surgery (ESS) is the primary mode of treatment for chronic sinus diseases. In this procedure, a proper assessment of the vital structures is very important to avoid further complications. In the present study, it has been suggested that determining the depth of the ethmoid roof is necessary to avoid injuring the bony lamella, which can lead to cerebrospinal fluid rhinorrhea.
The purpose of this study was to examine the diagnostic performance of real-time tissue elastography in detecting lymph node involvement in skin cancers. Methodology We retrospectively analyzed B-mode sonography and real-time elastography (RTE) images of 70 lymph nodes from 34 patients diagnosed with squamous cell carcinoma (SCC) or malignant melanoma (MM). In the Bmode examination, the appearance or loss of the hilar architecture in the lymph node, contour lobulation, and the presence of focal cortical thickening were evaluated. Elastography scores were classified according to the ratio of soft and hard areas across the lymph node on a 4-point scale system. Largely soft lymph nodes were scored as "1" and largely hard lymph nodes were scored as "4". Results When patients with SCC and MM were evaluated together, the sensitivity of elastography was 94%, specificity was 70%, and the accuracy rate was 86% in detecting lymph node involvement. When both tumor groups were evaluated separately, for SCC, the sensitivity of elastography was 90%, specificity was 61%, and the accuracy rate was 80% in detecting lymph node involvement. When the receiver operating characteristic (ROC) curve was taken, the area under the curve (AUC) was 0.78 for SCC. Elastography showed full compliance with pathology in lymph node metastases of MM and the AUC was 1.00. Conclusions Based on our findings, RTE provides important contributions to B-mode ultrasonography (USG) in evaluating lymph node metastases of skin cancers.
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