Purpose Review the literature concerning adrenal insufficiency (AI) and adrenal crisis (AC) in adolescents and young adults. Methods Searches of PubMed identifying relevant reports up to March 2022. Results AI is rare disorder that requires lifelong glucocorticoid replacement therapy and is associated with substantial morbidity and occasional mortality among adolescents and young adults. Aetiologies in this age group are more commonly congenital, with acquired causes, resulting from tumours in the hypothalamic-pituitary area and autoimmune adrenalitis among others, increasing with age. All patients with AI are at risk of AC, which have an estimated incidence of 6 to 8 ACs/100 patient years. Prevention of ACs includes use of educational interventions to achieve competency in dose escalation and parenteral glucocorticoid administration during times of physiological stress, such as an intercurrent infection. While the incidence of AI/AC in young children and adults has been documented, there are few studies focussed on the AC occurrence in adolescents and young adults with AI. This is despite the range of developmental, psychosocial, and structural changes that can interfere with chronic disease management during this important period of growth and development. Conclusion In this review, we examine the current state of knowledge of AC epidemiology in emerging adults; examine the causes of ACs in this age group; and suggest areas for further investigation that are aimed at reducing the incidence and health impact of ACs in these patients.
Supervising medical students to develop a research project can be challenging. Unless a student has prior experience in research, they may struggle to identify a research question that can be addressed by a novice researcher in a time-limited project. At the same time, when a project spans years of the degree, a student who has been offered an "off-the-shelf" idea may lose interest in the project and the assignment can become burdensome. We describe how a cohort of medical students were encouraged to focus their project ideas on a story of someone whose medical problem was of interest to them. Most students opted to conduct a literature review based on their "story". Here we present their stories and describe how they were led to this point in the process. DESIGN INSIGHTand impaired vision. She has had no time lately to attend her own GP appointments. As a result, her health is also declining. Research Question:While there is significant research on carer burden of those supporting people living with dementia, this is not the case for culturally and linguistically diverse (CALD) carers. What is the impact on the health of older carers of a CALD person living with dementia? MichaelWho: Michael is a 23-year-old in his final year of his undergraduate degree at university. He is a healthy and active young man, having grown up playing rugby, basketball, and touch football. He is a very sociable character and loves his lifestyle.What: Michael has no significant past medical history and rarely needed to visit his GP. But over a couple of weeks, Michael started to feel generally unwell, fatigued, and nauseous. He ignored these vague non-specific symptoms attributing them to being run down from university, which in the past had amounted to nothing and abated within a few days. A few months later, he noticed a small painless lump in his left testicle. Michael being the eldest child of three, felt too awkward about talking to younger family members for advice, so instead he left it for a few more weeks in the hope that it would spontaneously resolve. When the lump did not go away, Michael had to accept that something might be wrong and made an active decision to book an appointment with a GP. Aspect of Care:At the first consultation Michael was told that "it was all fine and nothing to worry about". But this did little to clear Michael's mind and he left with a sinking feeling that something was simply "not right". After battling with these feelings for a few weeks he decided to alert his family into what has been happening and he was again booked into see a GP. This time, the GP suspected it was a varicocele and wrote up a non-urgent referral to a urologist. The next available appointment was in three months. The urologist sent him off for a scrotal ultrasound. Again, the next available scan was a few days later. Upon review of the ultrasound, the urologist diagnosed Michael with testicular cancer and urgently referred him onto the oncologist. It was December 23 of that year when he was finally diagnosed. Michael went in f...
Teaching and learning of anatomy for medical students have been extensively studied. However, we believe that a 'gold-standard' of an anatomy teaching and learning model is difficult to establish as every educational institution faces unique. For the past ten years at the University of Notre Dame Australia, School of Medicine Sydney, the anatomy faculty has implemented evidence-based teaching strategies adopted from medical schools around the world and supported by timely student feedback to deliver cost-effective and sustainable anatomy learning. Student evaluations of this program have been positive and associated with improved summative anatomy results. This article describes ten principles pursued by our faculty, which we hope will help others in restructuring or enhancing their anatomy teaching and learning program.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2025 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.