The human brain is highly dynamic, supporting a remarkable range of cognitive abilities that emerge over the course of development. While flexible and dynamic coordination between different neural systems is firmly established for children, our understanding of brain functional organization in early life has been built largely on the implicit assumption that functional connectivity (FC) is static. Understanding the nature of dynamic neural interactions during development is a critical issue for cognitive neuroscience, with implications for neurodevelopmental pathologies that involve anomalies in brain connectivity. In this work, we delineate FC dynamics of neurocognitive networks in a sample of 146 youth from varied sociodemographic backgrounds. We apply independent component analysis, sliding time window correlation, and k-means clustering to resting-state fMRI data. Our analyses revealed six FC states that re-occur over time and that complement, but significantly extend, measures of static connectivity averaged across the experiment. Moreover, the occurrence and amount of time spent in specific FC states are related to the content of self-generated thought during the scan. We also found age-related increases in temporal variability of FC among neurocognitive networks. In addition, some connections are more variable over time than are others, including those between inferior parietal lobe and precuneus. These regions contribute to multiple large-scale systems and likely play a role in adaptive processes in early life. Taken together, these findings lay the groundwork for understanding how variation in the developing chronnectome is related to risk for neurodevelopmental disorders. Understanding how brain systems reconfigure with development should provide insight into the ontogeny of complex, flexible cognitive processes in adulthood.

No abstract

The purpose of this study was to explore the adoption and parenting experiences of lesbian and gay (LG) adoptive parents. Data for the present study are from a larger national cross-sectional survey of LG adoptive parents. Participants were recruited through advertisements placed in metropolitan LG newspapers, Web sites, and organizations across the country that serve LG individuals. This paper presents an analysis of the qualitative data gathered from 182 participants who responded to the following statement and two questions: 1. Write three short statements describing the biggest barriers or challenges that you faced in your efforts to become an LG adoptive parent. 2. What are the three biggest challenges you now face as an LG adoptive parent? 3. What are the three biggest joys you have experienced as an LG adoptive parent? The sample in this study was 54.9% female and 90% White. Thematic analysis was utilized to summarize the nature of the adoption experience from the LG parent perspective. Parents identified LG-specific barriers to becoming adoptive parents including perceived discrimination at all levels of the adoption process. Further, parents report a lack of role models to guide and mentor them. LG challenges included legal fears and struggles as they attempted to finalize both the initial and second-parent adoption.LG joys included being a role model to other parents, unanticipated increased extended family involvement, and unanticipated community support and acceptance.

Background Quality of life (QOL) is increasingly recognized as central to the broad construct of recovery in substance abuse services. QOL measures can supplement more objective symptom measures, identify specific service needs and document changes in functioning that are associated with substance use patterns. To date however, QOL remains an under investigated area in the addictions field, especially in the United States. Methods This study examines patterns and predictors of QOL at 1 and 6 months post treatment intake among 240 women enrolled in substance abuse treatment in Cleveland, Ohio. The World Health Organization Quality of Life (WHOQOL-BREF) measure was used to assess physical, psychological, social and environmental domains. Hierarchical multiple regressions were conducted to identify correlates of QOL at 6 months post treatment intake. Results All QOL domains across the follow up time points improved significantly. However, QOL scores across domains remained below those of healthy population norms. Trauma symptoms significantly predicted Physical and Psychological QOL. Among treatment process variables, alcohol use was the sole significant factor associated with QOL and only for Environmental QOL. Recovery support and friends support for abstinence were consistently associated with QOL across all four domains. Implications This study suggests the usefulness of the WHOQOL measure as an indicator of functioning in substance abusing populations. Findings underline the importance of helping women deal with trauma symptoms and develop support for recovery. Further research is needed on the longitudinal relationship between QOL and substance use patterns

No abstract