Аналізуючи літературні дані, встановлено, що переважна більшість ефемероїдів, поширених на території України, перебувають під прямим чи опосередкованим впливом людини, що призводить до прискорених темпів зменшення їх чисельності. Урбаністичний фактор впливає не лише на видовий склад популяцій, але й на їх абсолютні кількісні показники. Метою досліджень було вивчення флористичного складу рослин-ефемероїдів на території ландшафтного парку місцевого значення «Немирівське Побужжя» поблизу села Гвоздів Немирівського району Вінницької області. Матеріали і методи. Вивчення флористичного складу рослин-ефемероїдів території ландшафтного парку місцевого значення «Немирівське Побужжя» проводилося експедиційно-маршрутним методом, а також випадково-регуляторним способом-закладання облікових ділянок площею 1 м2. Систематична належність рослин визначалася за допомогою визначника. Рясність видів визначалася за шкалою Гульта-Друде (з доповненням А. А. Уранова та П. Д. Ярошенко). Коефіцієнт зустрічання (%) визначали за формулою: R= a x 100 / n.
Annotation. Medicinal plant St. John's wort (Hypericum perforatum L) is widely used in medicine in many countries of the world as a natural antidepressant, and due to its antitumor and cytotoxic effects. Research is being actively conducted on the use of St. John's wort in other areas of medicine. The purpose of the study is a marketing analysis of medicinal products that are registered in Ukraine with the active ingredient St. John's wort (Hypericum perforatum L.). The research material was data from the State Register of Medicinal Products of Ukraine in 2022, declared wholesale and retail prices in Ukraine as of October 2022. The research methods were frequency and content analysis. According to the ATS classification of medicinal products with the active ingredient St. John's wort on the pharmaceutical market of Ukraine, the presence of 4 groups has been established: A - agents affecting the digestive system and metabolism, N - agents affecting the nervous system, L - antineoplastic and immunomodulating agents, G-agents affecting the genitourinary system and sex hormones. According to the declared wholesale and retail prices as of October 2022, various forms of release of medicines were established, namely tablets, capsules, collections, solutions, herbs, drops, tinctures, syrups and balms. The cost of various dosage forms with the active ingredient St. John's wort was determined. It was established that the cost of 1 package ranges from UAH 10.57 to UAH 474.21. As a result of the content analysis, an assortment of medicinal forms registered on the territory of Ukraine and consisting of 27 trade names was established. The medical fees are presented by 5 TN and occupy 18.52% of the pharmaceutical market of Ukraine. According to the ATS classification, the largest group of drugs with the active ingredient St. John's wort is group A – drugs that affect the digestive system and metabolism. During the analysis of manufacturers of modern dosage forms it was established that the ratio of domestic and foreign production is 3:1, where domestic dosage forms make up 74%. In the future, it is planned to carry out a more detailed content analysis of drugs, taking into account accessibility for the consumer/patient and the development of new complex drugs that based on St. John's wort.
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