As there is no vaccination and proper medicine for treatment, the recent pandemic caused by COVID-19 has drawn attention to the strategies of quarantine and other governmental measures, like lockdown, media coverage on social isolation, and improvement of public hygiene, etc to control the disease. The mathematical model can help when these intervention measures are the best strategies for disease control as well as how they might affect the disease dynamics. Motivated by this, in this article, we have formulated a mathematical model introducing a quarantine class and governmental intervention measures to mitigate disease transmission. We study a thorough dynamical behavior of the model in terms of the basic reproduction number. Further, we perform the sensitivity analysis of the essential reproduction number and found that reducing the contact of exposed and susceptible humans is the most critical factor in achieving disease control. To lessen the infected individuals as well as to minimize the cost of implementing government control measures, we formulate an optimal control problem, and optimal control is determined. Finally, we forecast a short-term trend of COVID-19 for the three highly affected states, Maharashtra, Delhi, and Tamil Nadu, in India, and it suggests that the first two states need further monitoring of control measures to reduce the contact of exposed and susceptible humans.
This paper describes a traditional SIR type epidemic model with saturated infection rate and treatment function. The dynamics of the model is studied from the point of view of stability and bifurcation. Basic reproduction number is obtained and it is shown that the model system may possess a backward bifurcation. The global asymptotic stability of the endemic equilibrium is studied with the help of a geometric approach. Optimal control problem is formulated and solved. Some numerical simulation works are carried out to validate our analytical results.
In this paper, we formulate and study a new fractional-order SIS epidemic model with fear effect of an infectious disease and treatment control. The existence and uniqueness, nonnegativity and finiteness of the system solutions for the proposed model have been analysed. All equilibria of the model system are found, and their local and also global stability analyses are examined. Conditions for fractional backward and fractional Hopf bifurcation are also analysed. We study how the disease control parameter, level of fear and fractional order play a role in the stability of equilibria and Hopf bifurcation. Further, we have established our analytical results through several numerical simulations.
In this paper, we propose and analyze a fractional-order SIS epidemic model with the saturated treatment and disease transmission. The existence and uniqueness, nonnegativity and finiteness of solutions for our suggested model have been studied. Different equilibria of the model are found and their local and global stability analyses are also examined. Furthermore, the conditions for fractional backward and fractional Hopf bifurcation are also analyzed in both the commensurate and incommensurate fractional-order model. We study how the control parameter and the order of the fractional derivative play role in local as well as global stability of equilibrium points and Hopf bifurcation. We have demonstrated the analytical results of our proposed model system through several numerical simulations.
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