<p class="abstract"><strong>Background: </strong>The study aimed to compare the clinical efficacy of platelet rich plasma (PRP) and platelet rich fibrin (PRF) used with phosphosilicate putty during immediate post extraction implant placement and immediate loading.</p><p class="abstract"><strong>Methods:</strong> A prospective comparative clinical study was conducted on 20 adults. Two groups were made with 10 patients in each by random selection. Each patient required tooth extraction and replacement with immediate implantation and immediate loading. In Group 1 PRP was prepared from the patient's blood, mixed with alloplastic graft, and packed in peri-implant space and similarly in Group 2 PRF was prepared from the patient's blood and mixed with alloplastic graft in peri-implant space. All the patients were evaluated for postoperative pain, soft tissue analysis, implant mobility, and crestal bone height changes were observed for up to 6 months, using paired/independent t-test, and Chi-square test.</p><p class="abstract"><strong>Results:</strong> It was seen that for pain on 1st postop day Group 1 had shown superior results than Group 2 after 7 days both groups showed good soft tissue healing. No significant difference was found in both groups when seen for implant mobility. The difference in crestal bone height gain in the first 3 months of Group 2 showed a remarkable height gain than in Group 1. And at 6th month overall crestal height gain difference between both groups was non-significant.</p><p class="abstract"><strong>Conclusions: </strong>The autologous PRF can present new possibilities for enhanced healing and functional recovery over PRP during immediate post extractive implantation and immediate loading.</p>

<p class="abstract"><strong>Background:</strong> The aim of the study was to evaluate the clinical efficacy of demineralised freeze dried bone allograft (DFDBA) and platelet rich fibrin (PRF) membrane in immediate implant placement into debrided infected mandibular molar sockets.</p><p class="abstract"><strong>Methods:</strong> A clinical trial was conducted on 15 adult patients requiring tooth extraction and replacement with endosseous implants. Atraumatic tooth extraction was followed by thorough debridement of the socket prior to implant placement. Demineralized freeze dried bone allograft and PRF membranes were used for guided bone regeneration. Pain, signs of infection, vertical bone height measurements (IS-BIC) and stability of implants (torque values) were assessed using paired t test, analysis of variance (ANOVA) and Chi-square test.</p><p class="abstract"><strong>Results:</strong> Statistically significant reduction in pain from immediate post-operative (post-op) day to 1^st post-op day, 7^th post-op day to 4 months post-op (p=0.006) was seen. Infection was present preoperatively and absent post-op 1^st day, 7^th day and 4 month in all the subjects. The mean IS-BIC was 2.30±2.27 mm post-op and 0.75±0.74 mm at 4 months. Average height gain on mesial and distal side was 1.55 mm (p=0.009).</p><p class="abstract"><strong>Conclusions: </strong>With proper pre-op and post-op care, immediate implant placement along with DFDBA and PRF membrane in teeth exhibiting periapical pathology, is a cost effective, time saving and reliable treatment option.</p>

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