For sustainable boro rice production in Bangladesh, a balanced fertilization to improve the current soil condition caused by mono-application of inorganic fertilizers and appropriate rice variety selection are very crucial. Therefore, an experiment was conducted at the Agronomy Field Laboratory, Bangladesh Agricultural University, Mymensingh, during the boro season of December 2016 to May 2017 to evaluate the effect of integrated nutrient management on two boro rice cultivars. The varieties were BRRI dhan28 and BRRI dhan29 and eight kinds of nutrient management viz., control (no fertilizers), recommended dose of inorganic fertilizers (120-60-40 N, P2O5, K2O kg ha-1 + gypsum 60 kg ha-1 and ZnSO4 @ 10 kg ha-1), full dose of poultry manure @ 5 t ha-1, cowdung @ 10 t ha-1, poultry manure @ 2.5 t ha-1 + 50% prilled urea and full dose of other inorganic fertilizers, cowdung @ 5 t ha-1 + 50% prilled urea and full dose of inorganic fertilizers, poultry manure @ 2.5 t ha-1 + 75% prilled urea and full dose of inorganic fertilizers, and cowdung @ 5 t ha-1 + 75% prilled urea and full dose of other inorganic fertilizers. The experiment was laid out in a split plot design with three replications. Result showed that, yield and yield components of boro rice were significantly influenced by variety, nutrient management and interaction of variety and nutrient management. In respect of grain yield, BRRI dhan29 produced the maximum yield (5.46 t ha-1). BRRI dhan28 showed poor performance with all characters and gave the minimum yield (4.07 t ha-1). In case of nutrient managements, the highest yield and yield component were obtained from poultry manure @ 2.5 t ha-1 + 50% prilled urea and full dose of inorganic fertilizers and produced the maximum grain yield (5.70 t ha-1). In the interaction of variety and integrated nutrient management, the highest grain yield (6.83 t ha-1) and straw yield (7.61 t ha-1) was obtained from poultry manure @ 2.5 t ha-1 + 50% prilled urea and full dose of inorganic fertilizers with BRRI dhan29 variety. So, BRRI dhan29 with 2.5 t ha-1 poultry manure + 50% prilled urea and full dose of the recommended inorganic fertilizers might be a promising practice for boro rice cultivation.