Purpose: To assess the predictability of desired postoperative refractive outcomes using the SRK-II formula for intraocular lens (IOL) power calculation in children undergoing cataract surgery in eyes with a previous pars plana vitrectomy (PPV). Methods: In this retrospective study, 68 eyes of 66 children who underwent cataract surgery and IOL implantation in eyes that had previous vitrectomy between January 2008 and December 2017 were included. Data were collected on preoperative and postoperative characteristics. The Mann-Whitney test, Kruskal-Wallis test, and multinominal logistic regression were used for comparing the results. Results: Absolute prediction error (APE) in the cohort was 1.29 ± 1.13. Desirable refractive outcome with insignificant prediction error of less than 0.50 diopters (D) was found in approximately one-third of the children. Patients were further subdivided by magnitude of APE as ≥ 0.50 to ≤ 1.00 D and > 1.00 D. Age at the time of surgery, axial length, mean keratometry, silicone oil removal, IOL position, scleral buckle, and corneal suture did not affect APE and there was no significant difference between the groups ( P > .05). Conclusions: The mean APE of the SRK-II formula for IOL power calculation in pediatric eyes that had vitrectomy is comparable to that reported in the literature for routine pediatric cataract surgeries. Factors such as age, axial length, corneal power, IOL position (bag/sulcus), scleral buckle, corneal suture, and silicone oil removal done prior to surgery or along with cataract surgery did not affect the APE. [ J Pediatr Ophthalmol Strabismus . 2021;58(2):126–131.]

Purpose: To assess the visual outcomes and associated factors in pediatric patients undergoing cataract surgery following pars plana vitrectomy (PPV). Methods: A total of 52 eyes of 52 children who underwent cataract surgery and intraocular lens (IOL) implantation in previously vitrectomized eyes between January 2008 and December 2017 were included in this retrospective study. Descriptive and inferential statistical measurements (Chi-square test, Fisher's exact test, odds ratio, multiple logistic regression) were done. Results: The mean age at PPV was 11.3 ± 2.9 years. The most common indication for PPV was retinal detachment in 43 eyes (82.69%) and vitreous hemorrhage in 6 eyes (11.53%). The mean preoperative and postoperative best-corrected visual acuity (BCVA) was 1.31 ± 0.48 logMAR (logarithm of the minimum angle of resolution) units (20/400) and 0.69 ± 0.45 logMAR units (20/100), respectively; P < 0.001. The final visual outcome was good in 37 eyes (71.15%) and poor in 15 eyes (28.85%). In mean follow-up of 4 years, 42.3% developed posterior capsular opacification, 13.5% developed glaucoma, and 3.8% had retinal redetachment after cataract surgery. In the presence of macular pathology, the visual outcome was poor (aOR [adjusted odds ratio] = 4.26, P = 0.002). Conclusion: Cataract surgery with IOL implantation in vitrectomized eyes among children is a safe procedure and can improve visual acuity and quality of life. However, the extent of improvement is limited by macular pathology.

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