In a low-income country, P(H1N1)2009v infection in pregnancy is associated with considerable mortality. Delayed presentation to a tertiary care center, lack of awareness, and restricted access to treatment might have contributed to the high mortality.
A 31-year-old multiparous lady, gravida 3, para 2, live 1, 1 early neonatal death with second degree consanguineous marriage, presented to us at eight weeks for routine antenatal checkup.In her first pregnancy, she had delivered a preterm, male baby at 36 weeks gestation, which died after 4 days of life. At birth, baby was found to have dry, scaly skin all over the body, wide open mouth with protruding lip, hypoplastic ears and nose and contractures of fingers and toes. A clinical diagnosis of harlequin ichthyosis was made. The couple underwent genetic counseling, where they were explained about the genetic etiology of the problem and the risk of recurrence in subsequent pregnancies. Option of fetal DNA banking for prenatal diagnosis in next pregnancy was offered to the parents but was not done due to financial constraints in the family.Her second pregnancy was unremarkable and she delivered a healthy male baby at term with no stigmata of HI.
Inducing labour with a Foley balloon catheter rather than using oxytocin or prostaglandins is considered to be less risky if the uterus is scarred. It is not known if more fluid in the balloon is more effective without being more dangerous. Volumes of 80 mL and 30 mL were compared in 154 eligible women. Mode of delivery, duration of labour and delivery within 24 h were similar in both groups. However, the second group required oxytocin more frequently. Though more scar dehiscences occurred in the first group, the difference was not significant.
Background:
Women with Extra hepatic portal vein obstruction (EHPVO) are mostly young and belong to Asian countries. In the Indian subcontinent, 20–30% variceal bleeds are caused by EHPVO. Hence pregnancy is a concern in such patients. The objective of this study is to observe the maternal and neonatal outcomes in women with EHPVO.
Materials and Method:
Extra hepatic portal vein obstruction was studied retrospectively in 28 pregnancies in 20 women from Jan 2011 to July 2018 at a tertiary hospital in South India and the pregnancy outcomes were observed during this period. Institutional Review Board approval obtained.
Results:
The mean age of the women was 24.3 years and the mean age of diagnosis was 18.5 years. Splenomegaly, thrombocytopenia and anaemia were seen in 22 (78.5%), 17 (60.7%) and 8 (28.5%) of pregnancies, respectively. Rate of abortions and preterm deliveries were 2 (7.1%, n =28) and 10 (35.7%, n =28). There was one stillbirth (3.6%) in the study group. EHPVO was diagnosed in 25 (89.3%) women prenatally in our series. During pregnancy only one woman had variceal bleed, which was managed conservatively. Blood and blood product transfusion was required in 7(25%) of women and there was no maternal mortality.
Conclusion:
Pregnancies in EHPVO have good maternal and neonatal outcomes, provided they are taken care of by a multidisciplinary approach in a tertiary care centre.
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