Umbilical cord contains two arteries and one vein connecting fetus to the placenta and is responsible for blood flow between the two. It is surrounded by Wharton’s jelly which is a gelatinous substance and functions as adventitia layer of umbilical vessels, thereby providing insulation and protection to the umbilical cord. Umbilical cord abnormalities are associated with poor perinatal outcomes. Very few cases of absent Wharton’s jelly are reported in literature. Ours might be the 8th one in which we did a lower segment caesarean section for meconium stained liquor but the baby died after 12 hours.

Abstract:The study was undertaken to compare lowering of blood pressure in pregnant women with hypertensive emergency by IV Labetalol and IV Hydralazine and to find out which drug produces better effect. This prospective type of interventional study was conducted in SMS Medical College, Jaipur among 226 women admitted with SBP ≥ 160 or DBP ≥ 110 mmHg or both. Women divided in 2 groups (113 each) devided randomly: Labetalol (Group-A), Hydralazine (Group-B).We measured the difference between pretreatment and after treatment mean arterial blood pressure. Pretreatment mean arterial blood pressure was 127.40±40 and 126.61±6.475 mmHg in labetalol and Hydralazine group respectively. After treatment mean arterial blood pressure was 112.25±5.821 and 109.27±14.30 mmHg in labetalol and Hydralazine group respectively. Mean arterial blood pressure change was 15.14 ± 8.02 mmHg in labetalol group and 17.34 ± 13.42 mmHg in hydralazine group. (p=0.136, Not significant). Labetalol and Hydralazine both drugs are first line drugs in severe hypertension in pregnancy as in our study both drugs control blood pressure in similar way.

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Background: To study the effect of human immunodeficiency virus (HIV) infection on pregnancy outcomes and new born as mother to child transmission of HIV is a major route on new infections in children and compare it with HIV uninfected pregnancies.Methods: Prospective comparative study conducted on 40 HIV seropositive and 40 HIV seronegative pregnant women attending ANC and delivering in the department of obstetrics and gynecology, S. M. S. Medical College, Jaipur, Rajasthan, India.Results: CD4 count had no effect on birth weight of baby or term of delivery. HIV seropositive pregnancies were more prone to IUD, still birth and preterm birth (p=0.029). Mother to child transmission was 2.7%.Conclusions: HIV infection increases the risk of adverse foetal outcome in terms of intrauterine demise, still birth and preterm labour.