The majority of e-class hospitals in Indonesia still apply manual, non-computerized systems to conduct operational activities every day. This causes problems especially for hospital directors, because as a director requires a system that can evaluate the operations of the hospital. This problem was initiated due to the data of operational activities that are currently available are not well managed. This happens because there is no system for employees so that employees have difficulty managing data from each process. In this paper, we discuss Online Transaction Processing (OLTP) application development using the Scrum Framework. Scrum can address complex adaptive problems, by increasing productivity and creativity of all stakeholders involved. The test results with User Accepted Testing (UAT), Usability Testing and Scrum analysis based on the results of the development of the project show the OLTP system with the Scrum method has met the needs of the functional aspects and the development of the X hospital system