Lean Thinking and Six Sigma are quality management tools developed in an industrial context, where they have proven their usefulness for decades. More recently, these tools entered health care. Quite some literature on the application of these tools in health care has appeared since. This paper reviews this literature; more than 120 papers are studied and classified according to the nature of the paper: review, case study, strategy or tool description. Many case study papers were found. For these papers further analysis was made on the focus quality issue, the tools used and the area of implementation.