: Marine fungi are valuable and richest sources of novel natural products for medicinal and pharmaceutical industries. Nutrient depletion, competition or any other types of metabolic stress which limit marine fungal growth promote the formation and secretion of secondary metabolites. Generally secondary metabolites can be produced by many different metabolic pathways and include antibiotics, cytotoxic and cyto-stimulatory compounds. Marine fungi produce many different types of metabolite that are of commercial importance. This review paper deals about 187 novel compounds and 212 other known compounds with anticancer and antibacterial activities with a special focus on the period from 2011-2019. Furthermore, this review highlights the sources of organisms, chemical classes and biological activities (anticancer and antibacterial) of metabolites, that were isolated and structurally elucidated from marine fungi to throw a helping hand for novel drug development.
Thermophilic fungi have often been proposed as magnificent sources, since, they grow in extremely harsh temperatures, ranging between 20-50 °C. They have ability to produce industrially germane thermo-resistant enzymes that can endure the austere environment of industrialized procedures, and have outspread mercantile acceptability in food, paper, feed, pulp and also in textile industries. The isolates of numerous thermophilic fungi are sources of biotechnologically valuable enzymes like pectinases, laccases, xylanases, phytases, proteases and cellulases etc., which display high levels of temperature tolerances up to a maximum range of 72 °C. Despite lesser-known knowledge about them, they have already aided humans in many ways and still have lot more to give. In the subsequent years, the utilization of thermostable enzymes is anticipated to escalate exponentially due to their role in biofuels. In this review I describe about their isolation from their respective habitat, production of thermostable enzymes and their applications in industry, which helped scientists to break through the field of Industrial Biotechnology.
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