Benign recurrent intrahepatic cholestasis is an inherited and occasionally sporadic disease presents as recurrent episodes of obstructive jaundice without any obstruction in billiary channel with intervening symptom free periods. Here we are presenting a case of 20-year-old male with a recurrent jaundice and pruritus who later diagnose as BRIC.Faridpur Med. Coll. J. 2014;9(2): 108-110

Abstract:Pancreatitis is a common non-bacterial inflammatory disease caused by activation, interstitial liberation and auto digestion of pancreas by its own enzymes. Common causes of acute pancreatitis are gall stones, alcohol, drugs, trauma, viral infections and hypertriglyceridemia. Much is known about the causes of pancreatitis but huge experimental data available about understanding of its pathogenesis is still incomplete. Hypercalcemia as a cause of pancreatitis is rarely reported. Hypercalcemia is usually the result of Primary hyperparathyroidism (PHPT) and the most common cause of PHPT is parathyroid adenoma. It is thought that the increased calcium concentration in pancreatic juice resulting from hypercalcemia may prematurely activate proteases. Mutations in different genes have been proposed as well to justify why only some patients with primary hyperparathyroidism and hypercalcemia develop acute pancreatitis. Here we present a case of recurrent acute pancreatitis resulting from hypercalcemia due to parathyroid adenoma in a 38-year-old man. Hyperparathyroidism was suspected when despite severe pancreatitis calcium level remained high and parathormone level was grossly raised

<p><strong>Background:</strong> Trauma is the leading cause of disability in the first four decades of life and third most common cause of death. Spinal trauma poses considerable threats to survival and quality of life.</p><p><strong>Objective:</strong> Aims of this study is to assess the demographics, mode of trauma, hospital stay, complications, neurological improvement and mortality.</p><p><strong>Methods:</strong> Retrospective Cross sectional analysis of the records of spinal injury patients admitted in the Spine Unit of Bangabandhu Sheikh Mujib Medical University (BSMMU) Hospital from October 2003 to December 2013 was carried out. The demo­graphics, mode of trauma, involved vertebral level, co-morbid factors; neurological status and its improvement by Ameri­can Spinal Injury Association (ASIA) Score, duration of hospital stay and complications during hospital stay was assessed. Results were analyzed by SPSS.</p><p><strong>Results:</strong> Out of 1288 patients admitted, 192(14.90%) patients(range, 8-72 years) sustained spinal injuries and most (63.02%)of them were young (range, 21-40 years). Male to female ratio was 5:1. Cervical spine was most commonly ( 44.66%) affected followed by lumbar (35 .41 % ), thoracic (13 .54% ), thoraco-lumbar (06.25%) and Cervico-thoracic (03.13%) region. Fracture through intervertebral disc was most common in cervical spine. Among the common causes were road traffic accidents (44.47%), fall from height (29.69%), heavy weight bearing (14.58%) and assault with gunshot (07.29%). Paraparesis was most frequent (51.05%) clinical presentation followed by quadriparesis (45.83%). Significant number of patients (83.33%) required operative treatment (p&lt;0.05) and 09.89% were managed conservatively. Mortality rate (03.64%) was insignificant (p&gt;0.05%) and 03.12% patient refused to take treatment. Of these patients, 77.01 % had shown neurological improvement of at least one grade according to ASIA Score.</p><p><strong>Conclusion:</strong> Wide varieties of patients are encountered and managed varying from conservative to surgery. Carefully selected treatment provides the utmost outcome and reduces mortality.</p>

Probiotic formulation is useful in reducing symptoms of irritable bowel syndrome. To assess effectiveness of multistrain probiotics with standard treatment than standard treatment alone. This was a randomized control trial conducted in the Department of Gastroenterology, BSMMU, from July 2015 to June 2016. Patients with diagnosed case of IBS using Rome III criteria, absence of red flag sign like anemia, fever, weight loss, per rectal bleeding, nocturnal frequency, family history of IBD, cancer and age 18-55 years, no probiotics used in prior 3 months were included in the study. Patients were divided into group A (Standard treatment) and group B (Probiotics with standard treatment). Symptom severity scores especially for abdominal pain, global symptom severity were assessed at baseline, at one month interval during treatment for two months and one month post treatment. Mean age of the patients was 31.64 ± 9.72 years and 32.17 ± 10.03 years with no statistical significant difference with male female ratio of 4.2:1 and 3.06:1 in group A and group B respectively. Severity of abdominal pain, frequency of pain in every 10 days, severity of abdominal distension, satisfaction with bowel syndrome, frequency of open bowels per day gradually reduced in both groups but was higher in group B than group A (P<0.05). Passing mucus with motion was gradually reduced in both groups but the decrement was higher in group A than group B (p<0.05). Multistrain probiotics with standard treatment is more effective in reducing IBS symptoms than standard treatment alone. JCMCTA 2016 ; 27 (2) : 31- 38

SARS-CoV-2 corona virus infection (COVID-19) is a public health emergency of international concern causing many deaths. The aim of this study was to assess demography, clinical presentation, blood group, disease severity and outcome of COVID-19 infected patients in Bangladesh. This is a cross sectional, observational study of 436 COVID- 19 infected patients, confirmed by RT-PCR assay's on nasopharyngeal swab specimens, presented at Faridpur Medical College Hospital and Kurmitola General Hospital during the month of May to September, 2020. Data were collected in a preformed data sheet and analyzed for variables included demography, source of infection, spreading within family, clinical features, blood group, disease severity and outcome. Study showed mean age 41.27±16.65 years with slight male predominance (1.87:1), most were service holder (47%), source of infection was unknown (40%), from infected family members (35%) and working place (23%). In 44% cases, family members of infected index cases were unaffected. Common co-morbidities were Diabetes Mellitus (19.7%) and Hypertension (19%). Blood group of most (41.29%) was B positive. Disease spectrum ranged from asymptomatic (15%), mild (53%), moderate (19%) and severe (13%) disease. Common presenting symptoms were fever (72.2%), cough (42.9%) dyspnoea (29.6%), myalgia (22.9%), anorexia (17.9%), fatigue (17.4%), diarrhea (13.5%), headache (12.4%) and anosmia (12.4%). Majority (75.2%) had nonspecific (fever, mayalgia, fatigue) symptoms and in 16.28% cases it was the only presentation. Respiratory (61.9%) and GI (28.4%) symptoms presented either concomitantly or with nonspecific symptoms (55%). Majority (95%) of patients recovered and only 5% died. Faridpur Med. Coll. J. Jan 2020;15(2): 53-57