Effectiveness and therapeutic value of the doxycycline plus streptomycin and doxycycline plus rifampin schedules of treatment of human brucellosis have been assessed by carrying out a prospective study on Ill patients randomly distributed into two groups. Patients in group A were treated with doxycycline plus streptomycin sulphate and those in group B with doxycycline plus rifampin. The temperature of all patients reverted to normal, and 54 patients from group A (91.6%) and 45 from group B (86.5 %) achieved total recovery with a single therapeutic cycle. Two therapeutic failures and 3 relapses in group A (8.4%) and 7 relapses in group B (13.46%) were observed. The tolerance to both regimens was good. Although the combination doxycycline plus rifampin offers a more convenient oral administration, in the light of these results, until more extensive research is carried out, it should be considered as an alternative rather than a first choice in the treatment of human brucellosis.

Acute administration of octreotide to cirrhotic patients with portal hypertension, with or without ascites, did not produce any change in glomerular filtration rate or in estimated renal plasm blood flow. However the free water clearance decreased significantly. This effect, under chronic administration, could be clinically important and deserves further studies.

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La internacionalización exige a las organizaciones replantearse su accionar en el mercado nacional e internacional. De allí que, como parte de una filosofía organizacional, las empresas que establecen un compromiso con el crecimiento y desarrollo de la sociedad, han apropiado la logística verde como parte de su actuación en la cadena de suministro con el objeto de mitigar el daño en materia ambiental que las actividades que van desde la adquisición de recursos renovables y no renovables, hasta la distribución de un producto o servicio pueden causar. Mientras a su vez, la adopción e implementación de prácticas verdes genera una serie de ventajas y beneficios. Razón por la cual el objetivo de este artículo es analizar los beneficios de la logística verde en el comercio y los negocios internacionales.