The article is devoted to the current problems of obstetrics, perinatology and neonatology. The article presents a literary review and covers scientific views on the factors of births and hazardous factors that lead to transfer and prolonged pregnancy. The most common perinatal complications of a delayed pregnancy are stillbirth, asphyxia, and birth trauma. Neonatal morbidity in premature infants is 29% and perinatal mortality is 19%, which is higher than in preterm infants. If the pregnancy is 43 weeks or more, these rates will increase. All of these diseases are associated with a decrease in the fetal resistance to hypoxia due to the large size of the brain and morphological changes in the placenta. Therefore, the incidence of meconium aspiration syndrome and fetal distress syndrome at birth increases, leading to high perinatal morbidity and mortality.

The article discusses the state of the cardiovascular system in children who have had COVID-19, depending on the severity of the course of the infectious process. We conducted a retrospective analysis of the case histories of 88 children of various ages who were hospitalized with a confirmed diagnosis of a new coronavirus infection COVID-19 in September-November 2020.There were 48 boys (54.6%), girls - 40 (45.4%). According to the classification, the examined children were divided into 4 groups: pre-preschool period (1-3 years) - 9 (10.2%), pre-school period (from 3 to 7 years) - 32 (36.4%), junior school period ( 7-11 years old) - 29 (32.9%) and senior school period (from 12 to 16 years old) - 18 (20.4%) . An analysis of the characteristics of the course of COVID-19 depending on the severity showed that the moderate and severe course of the disease mostly developed in boys (58.5 and 60.0%), the mild course was typical for girls (66.7%).

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