Craniosynostosis is a condition characterized by the preterm fusion of cranial sutures in which one or more sutures close early, even before the completion of brain growth and development, leading to various facial anomalies. Crouzon syndrome, one among the Syndromic Craniosynostosis, is an autosomal dominant condition which is characterized as a triad of skull deformities, facial anomalies, and exophthalmos. The syndrome was named after French neurologist Louis Edouard Octave Crouzon in 1912, with a prevalence of 1 in 60,000. Here we report a case series of crouzon syndrome with genetic & syndromic review on craniosynostosis.