This article summarizes recent progress in our understanding of the reaction mechanisms leading to the formation of superheavy nuclei in cold and hot fusion reactions. Calculations are done within the Fusion-by-Diffusion (FBD) model using the new nuclear data tables by Jachimowicz et al. [At. Data Nucl. Data Tables 138, 101393 (2021)]. The synthesis reaction is treated in a standard way as a threestep process (i.e., capture, fusion, and survival). Each reaction step is analysed separately. Model calculations are compared with selected experimental data on capture, fissionlike and fusion cross sections, fusion probabilities, and evaporation residue excitation functions. The role of the angular momentum in the fusion step is discussed in detail. A set of fusion excitation functions with corresponding fusion probabilities is provided for cold and hot synthesis reactions.