Introduction: Papilledema is a common sign in ophthalmology and is typically associated with increased intracranial pressure (ICP) in neurological diseases. Since the beginning of the 20th century, some cases of papilledema have been reported in association with acute or chronic inflammatory neuropathies. Case Report: We describe a 42-year-old man with acute-onset inflammatory polyradiculoneuropathy and bilateral papilledema. Conclusions: Based on a personal case report and from an extensive review of the medical literature, we identify 2 distinct patterns. First, radiculoneuropathy may be a consequence of intracranial pressure (peripheral nerve involvement corresponding to a “false localizing sign”). Second, papilledema may occur after the onset of inflammatory neuropathy. For such cases, the pathophysiological mechanism remains unknown (eg, reactional inflammatory processes or actions of unknown autoantibodies) and requires further elucidation.

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PurposeBlepharospasm is defined as a located form of dystonia which is best medically treated with botulinum toxin injections.MethodsOur study concerned patients suffering from blepharospasm and operated of eyelid suspension because of botulinum toxin insufficiency, and their follow up over many years.ResultsThe mean time between blepharospasm diagnostic and surgery was 43.8 months. 76% of patients needed new toxin injections after a mean time of 3.5 months after surgery. A new surgery was performed because of late overcorrection for 28% of patients, with a mean time between the two surgeries of 64 months.Compared with previous studies, our patients population was similar, the patient rate retreated with toxin was high but lower than the 100% generally described. The long terme re‐operation rate was high in our study. This over‐correction could be linked to a blepharospam decreasing intensity after a many years evolution.ConclusionsMost patients operated of eyelid suspension for blepharospasm need new botulinum toxin injections but some can be over‐corrected in case of pathology relief after many years of progression.

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