The vasodepressor prostaglandinA, (PGA,) was administered by i.v. infusion till delivery or to a maximum of 24 hours to 27 women (3440 weeks pregnant) with severe pregnancy induad hypertension. IntrPccrvical prostaglandin E, gel wps applied as a supplement to PGA, infusion to ripen the unfavourable a d x in selected cases. The patients were assigned at random to one of three equal groups according to the time of gel @ Institute of Obstetrics and Gynaecology Trust, 1989 J Obstet Gynaecol Downloaded from informahealthcare.com by University of North Carolina on 11/04/14 For personal use only.Ylikorkala 0. and Makila U. M. (1985). Prostacyclin and thromboxane in gynecology and obstetrics. American Journal of Obstetrics and Gynecology 1% 318-329.

Endometritis is one of uterine disorders in dairy cows causing low fertility. This study explored effects of intrauterine (IU) infusion of Cefazolin on endometrial cytology and reagent test strips parameters (leukocyte esterase [LE] and pH) in bovine subclinical endometritis. A total of 90 cows at 49-56 days in milk (DIM) diagnosed for subclinical endometritis were divided randomlyinto three groups, group I (n = 35), treated with IU infusion of 2 grams Cefazolin (Zinol ®, Pharco) diluted with 50 ml saline; group II (n = 28), treated with IU infusion of 2 gramsCephalexin (Ceporex®, GlaxoSmithKline) diluted with 50 ml saline; group III (n = 27), cows kept as untreated control. Cytological examination and reagent test strips were performed in uterine material derived with the cotton swab technique before treatment program and repeated two times later, in 10 days interval. The cows were artificially inseminated at first oestrous after the end of treatment program and conception rates were evaluated. After the end of treatment program, polymorphonuclear cells (PMN) decreased significantly (P <0.05) in Cefazolin and Cephalexin groups (3.23% and 4.39% respectively) compared tocontrol (24.89%) group, also means of LE in these groups became significantly (P<0.05) lower. The Ph value decreased after treatment, this reduction was significant after the first dose of Cefazolin, while in Cephalexin reduction of pH became significant after second dose. Cefazolin had conception rate (77.14%) significantly (P<0.05) higher than cephalexin and control groups (57.14% and 25.93% respectively). Cefazolin and Cephalexin decrease uterine PMN, LE concentration. The pH value after treatment by Cefazolin was lower than in Cephalexin. Moreover, treatment with Cefazolin resulted in a significantly higher conception rate. Thus, Cefazolin is recommended for the treatment of subclinical endometritis in dairy cows.

The study was performed to find out the relation between the uterine bacterial contaminations without clinical signs and postpartum (PP) reproductive performance of dairy cows. So that, uterine bacterial samples from postpartum dairy cows total (n = 44) were taken at 3rd, 15th and 30th day, and the bacterial count and score were applied. The animals were grouped to low, medium and high uterine bacterial contamination (15, 15, and 14 cows for each group respectively) according to score. Results revealed that uterine bacterial score (UBS) was decreased by the time in 3rd, 15th and 30th day (PP) for Low bacterial contamination group (5.73, 2.80, and 1.20 respectively), for Medium bacterial contamination group (7.80, 2.73,  and 1.47 respectively), and for High bacterial contamination group (9.29, 6.57, and 2.21 respectively). Also, it revealed that there was a significant increase (P<0.05) in the duration of lochia in High than Low and Medium bacterial contamination groups. At 3rd day (PP), uterine location in all cows was represented in the abdominal cavity, but at15th day (PP), uterine involution as reaching to its normal non pregnant position in pelvic cavity was delayed in High (50%) than Low (80 %,) and Medium (53.30%) UBS groups. Moreover, at 30th day, uterine location in all cows was represented in pelvic cavity. The first estrus (PP) was significantly shorter in Medium, Low than High UBS groups. The number of services per conception showed a significant increase in High than in Low and Medium UBS groups. Also, at the 90th day (PP), the conception rate was lower in High UBS group than Low UBS group and Medium UBS group. We conclude that there was a relation between postpartum uterine bacterial contamination without clinical signs especially high contamination and reproductive performance in cows.