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In this paper, key aspects of constructing a hydrodynamic model of high-pressure air injection into Bazhenov source rocks were highlighted. Most of them are associated with the choice of pseudo-components of kerogen required to describe thermal decomposition and oxidation of kerogen and needed for construction of a kinetic model. Sensitivity analysis was carried out. As a result, high sensitivity of output to the change in the content of components reflecting the presence of kerogen in the formation and its participation in oxidation processes and thermal decomposition was confirmed. Based on the above, a list of experimental studies was formulated, which must be carried out to determine the parameters of numerical simulation and to evaluate the effectiveness of the high-pressure air injection method. High-pressure ramped temperature oxidation of kerogen was carried out. As a result, temperature profiles, gas composition, and volume of generated/displaced fluids were obtained. 24.8 g of water-oil emulsion were generated from 92 cm3 of rock. Kerogen in the sample was completely converted, which was confirmed by the results of conducted pyrolysis studies.