Background: Silver has been widely used for disinfection because of its well known antibacterial properties. Recently, silver nanoparticles have shown higher activity killing and inhibiting bacterial reproduction. In the present work we obtained silver nanoparticles highly dispersed over nanostructured titania in order to enhance bacterial sensitivity.Materials and methods: Four different Titania-based nanoparticles were synthesized by the Sol-Gel process using Ag 2 SO 4 , AgCl, AgNO 3 and CH 3 COOAg as silver precursor. All the materials were characterized by FTIR, UV-Vis and XPS, TEM microscopy, EDS, also BET and DRX analysis were carried out.Results: Amorphous materials were apparently obtained. Ag-TiO 2 nanoparticles were tested against several Gramnegative and Gram-positive bacteria including enterophatogenic Escherichia coli and highly resistant strains such as methicillin-resistant Staphylococcus aureus and they showed sensibility in most of cases.Conclusions: Supported silver nanoparticles represent a suitable way to obtain highly dispersed active silver over higher surface area. This approach allows it use as efficient bactericide since lower silver amount can be employed. Journal of Nanomedicine & NanotechnologyJ o u rna l of N a n o m ed icine & N a n o te chnolo g y

The influence of bond-coating on the mechanical properties of plasma-spray coatings of hydroxyatite on Ti was investigated. Plasma-spray powder was produced from human teeth enamel and dentine. Before processing the main apatite coating, a very thin layer of Al2O3/TiO2 was applied on super clean and roughened, by Al2O3 blasting, Ti surface as bond-coating. The experimental results showed that bond-coating caused significant increase of the mechanical properties of the coating layer: In the case of the enamel powder from 6.66 MPa of the simple coating to 9.71 MPa for the bond-coating and in the case of the dentine powder from 6.27 MPa to 7.84 MPa, respectively. Both tooth derived powders feature high thermal stability likely due to their relatively high content of fluorine. Therefore, F-rich apatites, such those investigated in this study, emerge themselves as superior candidate materials for calcium phosphate coatings of producing medical devices. The methods of apatite powder production and shaping optimization of powder particles are both key factors of a successful coating. The methods used in this study can be adopted as handy, inexpensive and reliable ways to produce high quality of powders for plasma spray purposes.

In the online and printed versions of the original article, there was a typographical error in I. Peker's name. His name is spelled correctly above. This error occurred in both the html and pdf versions of the online article.

Nonsteroidal anti-inflammatory drugs (NSAIDs) are among most commonly prescribed medications worldwide. NSAIDs play an important role due to their pronounced analgesic potency, anti-inflammatory effects, and lesser side effects compared to opioids. However, adverse effects including gastrointestinal and cardiovascular effects seriously complicate their prolonged use. In the present work we prepare SiO2-based nanoparticles with ketorolac, for controlled release proposes. The nanomaterials were prepared by the sol-gel technology at acidic conditions and two different water/alcoxide ratios were used. FTIR spectroscopy was performed in order to characterize the solids and drug-SiO2interactions. Thermal analysis and nitrogen adsorption isotherms showed thermal stability of the drug and confirmed the presence of particles with high surface area. Transmission electron micrographies of the samples showed the nanosize particles (20 nm) forming aggregates. Drug release profiles were collected by means of UV-Vis spectroscopy and kinetic analysis was developed. Release data were fitted and 1 : 8 sample showed a sustained release over ten hours; 90% of the drug was delivered at the end of the time.