Abstract:The accuracy of three dimensional predictions of soft tissue changes following surgical correction of facial asymmetry has been evaluated in this study. The preoperative (T1) and 6-12 months postoperative (T2) CBCT scans of 13 patients were studied. All patients had surgical correction for facial asymmetry as part of the multidisciplinary treatment protocol.The magnitude of surgical movement was measured; virtual surgery was carried out on the preoperative scans using Maxilim software. The predicted soft tissue changes were compared to the actual postoperative appearance (T2) at specific anatomic facial regions. Mean (signed) distances and the mean (absolute) distances between the predicted and actual 3D surface meshes for each region were calculated. One sample Student t-test was applied. Additionally, a novel directional soft tissue analysis was applied to analyse the accuracy of the prediction of soft tissue. The results showed that the distances between the predicted and actual postoperative soft tissue changes were within 2.0mm (p<0.05) at all regions. The predicted facial morphology was narrower than the actual surgical changes at the cheek regions. Three dimensional soft tissue prediction for the correction of asymmetric cases is clinically acceptable using Maxilim software. Introduction: