From the herb Stephania hernandifolia (family Menispermaceae) growing in Transcaucasia, via its sparingly soluble hydrochloride, we have isolated a base with the composition C20H27OsN , mp 114-115 ° C (from ether), 144.5 ° C (from methanol), [aiD --97"9° (c 0.7, ethanol), mol wt 370 (Rast); hydrochloride with mp 199.5-200.5 ° C (from ethanol). It contains three OCH 3 groups (signals in the NMR spectrum at 3.38, 3.47, and 3.65 ppm), two OH groups (3300 and 3520 cm -~) and an NCH~ group (signal at 2.46 ppm). The presence of these functional groups was also shown analytically. Absorption bands at 1590 and 1630 cm -1 in the IR spectrum confirm the presence of an aromatic ring in the molecule. EtOH UV spectrum: Xma x 216 and 285 n~ (log e 3.94 and 3.48). This alkaloid has not been described in the literature and is new.The Hofmann degradation of the alkaloid yielded a methiodide with mp 178-180 ° C and a desbase with mp 114-115 ° C giving no depression of the melting point in admixture with the desbase of hernandoline [1]; the two substances gave spots with the same Rf value in TLC on alumina in an ether-methanol (25 : 168) system.On acetolysis, the desbase formed a substance with mp 163-164 ° C identical with the diacetoxydimethoxyphenantrene obtained from hernandoline [1].

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