CASE STUDY: GASTRIC MUCOSA-ASSOCIATED LYMPHOID TISSUE (MALT) LYMPHOMA
Extranodal marginal zone lymphomas of mucosa-associated lymphoid tissue (EMZL-MALT) have been linked to chronic immune stimulation due toinfection or autoimmune stimuli.The causal association between Helicobacter pylori(HP) and gastric MALT lymphoma has been well demonstrated. HPeradication with antibiotics has emerged as the standard therapy for early stage HPpositive gastric MALT lymphoma.High response rates and long-term survival have been reported inpatients with localized gastric MALT lymphomatreated with low-doseradiationtherapy.Monoclonal antibody and chemotherapy are reserved forpatients failing or recurring after RT and those with advanced stage disease.
Key words: mucosa-associated lymphoid tissue, gastric lymphoma
plan. In 2 cases acute imaging was not performed due to severe treatment-related side effects.There were no significant differences between baseline and acute 82Rb PET scans although we did register a non-significant decline in PET imaging did not show any immediate effect on perfusion parameters after doxorubicin exposure, a subgroup of patients did demonstrate a marked decrease in CFR. In our future studies, we will investigate whether these acute changes translate into an increased risk of myocardial fibrosis and HF at 12 month follow-up.
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