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The authors present a gastric mucosal biopsy technique with use of a nasogastric catheter and biopsy forceps after double-contrast upper gastrointestinal fluoroscopy in patients with clinical symptoms of dyspepsia. In 51 patients (18 men and 33 women, aged 27-73 years [mean, 46 years]), 136 aggregates (specimens composed of the two pieces of mucosal tissue obtained in each region) ranged from 0.1 to 0.6 cm in diameter. All but three specimens were of adequate mucosal depth. No complications secondary to bleeding resulted.

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