Relevance. There is currently an active introduction of information technologies in various spheres of human life, especially medicine. And dentistry is no exception, which undoubtedly increases dental care level. The article describes a computer program for the preclinical prediction of caries development risk in permanent teeth in children after the eruption. The program allows for identifying disease development risks allowing you to carry out preventive measures in advance. Purpose: Development of a simple and accessible computer system providing information support to dentists in dental caries risk identification and timely prescription of preventive measures.Material and methods. Obtaining and processing information on the clinical and laboratory parameters of caries-resistant children with mixed dentition was the first stage for creating a computer system. The statistical analysis detected the factors influencing the carious process development risks and determining critical values. A developer wrote a program, according to the requirement specifications, which simulates possible carious process development risks.Results. The received software allows for identifying caries development risks at the preclinical stage, scheduling checkup times and recommending duly caries preventive measures.Conclusion. Software program experimental implementation showed a high coincidence between the clinical picture and PC program approbation after a two-year observation of caries-resistant children with mixed dentition.