Propofol is a popular intravenous induction agent, hypotension is known complication of propofol, hence priming technique is adopted to reduce the induction dose and hence reduce the incidence of hypotension. Current study is undertaken to evaluate the haemodynamic changes with bolus dose and priming dose of propofol. METHODS: the study population is divided into two groups -PRIMING GROUP: After calculating the total dose of Propofol induction agent (2mg/kg) 20% was injected as bolus and remaining drug is administered till the loss of eye lash reflux and verbal response at the rate of 30mg/10sec. NON PRIMING GROUP: intravenous injection of propofol bolus (2mg/kg) iv in 30 seconds was given. RESULT: A mean induction dose of Propofol required in priming group is 88.26mg and in non-priming group it is 106.28mg. Reduction in dose requirement in priming group is by 16.74%.Haemodynamic stability was better in non-priming group. Complications like apnoea, involuntary movements, were seen in both the groups. CONCLUSION: Induction dose of Propofol is reduced in priming group and there is greater fall of blood pressure compared to non-priming group, both groups had fewer side effects like apnoea and involuntary movements.

Introduction: Induction of anaesthesia in paediatric age group is more challenging when compared to adults because of non availability of proper intravenous line, inhalational induction agents and non cooperation of the child.Inhalational Anaesthesia is the preferred technique of induction in the paediatric age group. Study objective was to find out induction time for halothane and sevoflurane in children aged between 2 years and 12 years Material and methods: A total of 79 paediatric patients in the age group between 2 years to 12 years undergoing surgery under general anaesthesia were selected they were randomised to two groups using closed envelope method. GROUP H: induction was done with Halothane and GROUP S: induction was done with Sevoflurane Results: Induction time and heart rate changes were observed. Induction time was 2mins and 8sec in halothane group and 1min and 17 sec in sevoflurane group was observed. Heart rate changes in halothane group was 116/ min and in sevoflurane group it was 130/min. Conclusion: We conclucled that sevoflurane is a faster induction agent than halothane and showed more heart rate changes at the time of induction. The Heart rate decrease was more with Halothane Group than Sevoflurane.