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The basement of the northeastern periphery of the East-European Craton (ЕЕС) is composed of volcanic-sedimentary sequences, volcanic rocks, granitoids, and rare ophiolite complexes. Geochronological data constrain their age from ca. 750 to 500 Ma, and there is a consensus that these rocks represent relicts of a late Neoproterozoic-Cambrian Pre-Uralides-Timanides orogeny. Combining new integrated isotopic (U-Pb, Lu-Hf) and trace-element data (TerraneChrone ® approach) on detrital zircons from sandstones of the lower Cambrian Brusov Formation in the Mezen basin (White Sea region in the northeastern periphery of the EEC) with available studies on detrital zircons from Neoproterozoic-middle Cambrian (meta) sedimentary units of the northeastern periphery of the EEC allow us to conclude that (1) the onset of the Arctida-Baltica collision can now be constrained to the time interval between ca. 540 and 510 Ma and (2) the Ediacaran-early Cambrian Mezen sedimentary basin was a basin on the Timanian passive margin of Baltica up to 540 Ma, but was not a foreland basin of the Pre-Uralides-Timanides orogen. Paleozoides of fold-nappes belts in the framing of East-European Craton (EEC) Me So-andNeoproterozoic filling of riftogenic structures (rifts, aulocogens, etc.) within the EEC Me so-and Neoproterozoic complexes, and rare reworked Archean-Paleoproterozoic complexes of relics of accretionary and collisional belts of north-western and western parts of the EEC Complexes of the Meso and Neoproterozoic accretionary belts and collisional orogens Complexes of the Paleoroterozoic collisional orogens Paleoproterozoic complexes of Fennoscandia, Volga-Uralia and Sarmatia Nonuniformly metam orphosed Neoproterozoic to Middle Cambrian complexes: Pre-Uralides-Timanides of Western Urals and Timan-Pechora-Barents Sea Region, and their ages analogues of near-Uralian part of EEC and Scandinavia (Finmarken and the lowest units of the Caledonian nappes), and Cadomides-Avalonides of the southern and SE frame of EEC Pre-Uralides-Timanides: a -mostly sedimentary complexes;