Наведено результати досліджень з інтродукції та введення в культуру видів, які потребують специфічних умов вирощування. Вивчено біологічні особливості таких цінних лісових видів, як Carex brevicollis DC, Thymus serpyllum L. та Malva excisa Rchb., що забезпечить успішне збереження їх генофонду й послужить основою для подальшої розробки технологій вирощування для отримання лікарської сировини.

ВИВЧЕННЯ АНТИБАКТЕРІАЛЬНИХ ВЛАСТИВОСТЕЙ КОМПЛЕКСНОГО АНТИБІОТИЧНОГО ПРЕПАРАТУВ статті наведено результати дослідження експериментальної композиції, яка містила енрофлоксацин (5%) та сульфадиметоксин (20%). МІК коливалася від 0,20±0,12 мкг/см 3 у відношенні до E. coli 1257 до 0,4±0,10 мкг/см 3 у відношенні до Clostridium perfringens. МІК експериментальної композиції була найнижчою у відношенні до Staphylococcus aureus Р209 (0,80±0,05 мкг/см 3 ), Proteus vulgaris (0,20±0,15 мкг/см 3 ), Clostridium perfringens (0,32±0,10 мкг/см 3 ).При вивченні зон затримки росту диско-дифузійним методом нами встановлено, що всі досліджувані штами були високочутливими як до енрофлоксацину, так і до експериментальної композиції.Ключові слова: антибіотичний препарат, антимікробна дія, форхінолони, Мінімальна інгібуюча концентрація (МІК), експериментальна композиція * Аспірант, науковий керівникд-р.вет.наук Айшпур О.Є.

Background. Biliary cystadenomas and cystadenocarcinomas are rare cystic tumors of the liver. Complicated differential diagnostics for simple cysts often leads to errors in surveillance of patients with these tumors. Cystadenoma and cystadenocarcinoma should be suspected upon detection of single or multilocular cystic neoplasms of the liver with septa and blood flow loci  in the cyst wall, especially in middle-aged women. The localization of the tumor is critical. The most common localization is segment IV of the liver. Urgent intraoperative biopsy is required to determine the extent of surgery.Case description. Clinical observations with analysis of the examination and treatment data of two female patients aged 38 and 56 were presented. Both clinical observations illustrate the underestimation of the preoperative examination data that served as a ground for diagnosis of liver cysts with inadequate extent of surgery. In the first case, the resection was incomplete, and, as such, the biliary cystadenoma recurred in the resection area, the capsule of the neoplasm was ruptured and an encysted fluid collection was formed. In the second case, lack of histological examination of the excised neoplasm, due to confidence in its morphological verification as a cyst, resulted in cystadenoma recurrence in the resection zone with metastasis to the contralateral lobe of the liver.Conclusion. Hepatic cystadenomas and cystadenocarcinomas are often misdiagnosed as simple cysts. These tumors should be suspected in central localization of the tumor in the liver, especially in young women. The clinical and instrumental symptomatology and radiological semiotics of the disease require careful evaluation. The recurrence of a cystic lesion in the resection zone in a patient previously operated for a hepatic cyst serves as an additional signal for detecting biliary cystadenoma. Rational strategy for surgical management of cystic liver lesions should include hepatectomy within healthy tissues (both anatomical and atypical) with mandatory intraoperative ultrasound and urgent histological examinations.

Doctor of Agricultural Sciences, Professor Volodymyr Yukhymovich Nedava (1925–2009) made a significant contribution to the development of selection, genetics and biotechnology in animal husbandry in Ukraine. His efforts laid the foundation for biotechnological foundations of farm animal reproduction and modern breed theory, substantiated the use of heterosis in livestock, effective methods of improving the brown Carpathian breed, simplified the method of assessing breeding animals for feed production. Goal. To analyze the directions of scientific activity of Doctor of Agricultural Sciences, Professor V. Yu. Nedava in the context of development of research in nanobiotechnology and to generalize its main achievements in developing the theory and methodology of application of ultra fine silica in media for cryopreservation of sperm farm animals. Methods. General scientific (analytical-synthetic, logical, systemic), biographical and source methods. The source base of the research covers a wide range of materials, which are based on archival documents and primary sources, scientific works (publications), reports and memoirs of colleagues about the talented scientist. Results. At the initiative and direct participation of V. Yu. Nedava, a method was developed for the treatment of bull semen, which differed from the conventional one in that in order to stabilize the biological value, to the freshly obtained sperm before dilution is added UFS at the rate of 3–30 mg per 1 billion sperm. Later, Professor V. Yu. Nedava and co-authors published the results of research on the use of fine pyrogenic UFS (Aerosil) as a stabilizer of the biological value of bull sperm, which was confirmed by higher fertility rates of heifers after insemination with Aerosil sperms (5.8% higher compared to control). Continuation of the initiated research of V. Yu. Nedava on the use of ultra fine silica to stabilize the cell surface of reproductive gametes was research on improving the technology of in vitro embryo formation and cryopreservation of male epididymal sperm using nanomaterials, which began in 2007. Conclusions. A number of scientific works of Professor Volodymyr Yukhymovich Nedava testify to his talented organizational and scientific character traits, which have a continuation in our time. V. Yu. Nedava initiated the development of the concept of VDK processing of semen of farm animals, determined their purpose in the system of conservation of genetic resources of farm animals, substantiated the importance of using such materials as the main link in the conservation of farm animals.