The present work was conducted to evaluate the comparative efficiency of certain phenol compounds (Salicylic acid, Benzoic acid, Acetylsalicylic acid and Sodium benzoate) on certain biological aspects of the Mediterranean fruit fly (MFF), Ceratitis capitata and the peach fruit fly (PFF) Bactrocera zonata under laboratory conditions. Salicylic acid and acetylsalicylic acid showed the same record on larval duration of MFF (10.5 days) and lowest record of % pupation of 70.5 and 75.8%, respectively. Also, control recorded the lowest pupal duration 8.1 days and highest average of fecundity (27.9 eggs/female), daily rate of oviposition (11.5 eggs/female/day), the total of deposited eggs of 1628.3, % hatchability 96.7% and longevity of males 27.5 days, whereas sodium benzoate showed the highest average of oviposition period (31.1 days) and high female longevity 35.7 days for MFF. Larval duration of PFF significantly showed the shortest period of 7.6 days and highest % pupation 100% with larval diet treated with sodium benzoate. Control showed the shortest pupal duration 7.8 days and highest average of fecundity (22.8 eggs/female), daily rate of oviposition (8.6 eggs/female/day), the total of deposited eggs of 1454.7, % hatchability of 92.3% and longevity of males (45.1 days). But, sodium benzoate showed the highest period of oviposition 38.8 days and females longevity 54.5 days.