The present study has been carried out to evaluate the concentration of copper (Cu) and vanadium (V) elements in the muscle, skin, and gill tissues of Tylosurus crocodilus (Belonidae), an edible fish, in the Bahregan region which is located in the northern part of the Persian Gulf. For this purpose, 18 fish samples in three different length groups (small, medium, and large) were randomly collected in Bahregan region. Tissues were separated and concentration of the heavy metals was determined by atomic absorption. The results showed that mean concentration of Cu and V were 0.2851 ± 0.10036 and 1.1368 ± 0.12405, 0.1117 ± 0.02322 and 2.5091 ± 1.14201 and 0.1803 ± 0.03204 and 3.3133 ± 1.05995 µg g -1 dry weight, in skin, muscle and gill tissues, respectively. Also, the results revealed a significant positive correlation between the standard length and Cu concentration in the muscle and gill tissues (P ≤ 0.05), as well as between the standard length and V concentration in all the tissues (P ≤ 0.05). The results indicated that the concentration of V was higher than the World Health Organization (WHO) standard but the concentration of Cu was lower. It is therefore highly recommended that usage of this carnivore species in the studied area is limited because of the high accumulation of V in its muscle tissue.