Personal protective clothing is critical to shield users from highly infectious diseases including COVID‐19. Such clothing is predominantly single‐use, made of plastic‐based synthetic fibers such as polypropylene and polyester, low cost and able to provide protection against pathogens. However, the environmental impacts of synthetic fiber‐based clothing are significant and well‐documented. Despite growing environmental concerns with single‐use plastic‐based protective clothing, the recent COVID‐19 pandemic has seen a significant increase in their use, which could result in a further surge of oceanic plastic pollution, adding to the mass of plastic waste that already threatens marine life. In this review, the nature of the raw materials involved in the production of such clothing, as well as manufacturing techniques and the personal protective equipment supply chain are briefly discussed. The environmental impacts at critical points in the protective clothing value chain are identified from production to consumption, focusing on water use, chemical pollution, CO 2 emissions, and waste. On the basis of these environmental impacts, the need for fundamental changes in the business model is outlined, including increased usage of reusable protective clothing, addressing supply chain “bottlenecks”, establishing better waste management, and the use of sustainable materials and processes without associated environmental problems.

The COVID‐19 pandemic highlighted the need for rapid tools and technologies to combat highly infectious viruses. The excellent electrical, mechanical and other functional properties of graphene and graphene‐like 2D materials (2DM) can be utilized to develop novel and innovative devices to tackle COVID‐19 and future pandemics. Here, the authors outline how graphene and other 2DM‐based technologies can be used for the detection, protection, and continuous monitoring of infectious diseases including COVID‐19. The authors highlight the potential of 2DM‐based biosensors in rapid testing and tracing of viruses to enable isolation of infected patients, and stop the spread of viruses. The possibilities of graphene‐based wearable devices are discussed for continuous monitoring of COVID‐19 symptoms. The authors also provide an overview of the personal protective equipment, and potential filtration mechanisms to separate, destroy or degrade highly infectious viruses, and the potential of graphene and other 2DM to increase their efficiency, and enhance functional and mechanical properties. Graphene and other 2DM could not only play a vital role for tackling the ongoing COVID‐19 pandemic but also provide technology platforms and tools for the protection, detection and monitoring of future viral diseases.