An intrahepatic arterioportal fistula is a rare cause of portal hypertension and variceal bleeding. We report on a patient with an intrahepatic arterioportal fistula following liver biopsy who was successfully treated by hepatectomy after unsuccessful arterial embolization. We also review the literature on symptomatic intrahepatic arterioportal fistulas after liver biopsy. A 48-year-old male with bleeding gastric varices and hepatitis B virus-associated liver cirrhosis was transferred to our hospital; this patient previously underwent percutaneous liver biopsies 3 and 6 years ago. Abdominal examination revealed a bruit over the liver, tenderness in the right upper quadrant, and splenomegaly. Ultrasonographic examination, computed tomography, and angiography confirmed an arterioportal fistula between the right hepatic artery and the right portal vein with portal hypertension. After admission, the patient suffered a large hematemesis and developed shock. He was treated with emergency transarterial embolization using microcoils. Since some collateral vessels bypassed the obstructive coils and still fed the fistulous area, embolization was performed again. Despite the second embolization, the collateral vessels could not be completely controlled. Radical treatment involving resection of his right hepatic lobe was performed. For nearly 6 years postoperatively, this patient has had no further episodes of variceal bleeding.
We describe a 50-year-old man with a secondary aortoduodenal fistula who presented with high fever and right leg pain one year after undergoing an aortoiliac bypass with a polyester graft. Gangrene had developed in the right ankle, and contrast-enhanced computed tomography (CT) revealed that the graft had penetrated the third duodenal segment and obstructed the right graft limb. Esophagogastroduodenoscopy confirmed that the graft had perforated the duodenum. A preoperative diagnosis of aortoenteric fistula can be very difficult. In spite of the lack of gastrointestinal bleeding in this case, we directly diagnosed secondary aortoduodenal fistula preoperatively using computed tomography and esophagogastroduodenoscopy. Secondary aortoenteric fistulae should be suspected when a patient with an aortic prosthesis shows symptoms in the lower limb.
A 15-year-old, woman, Crohn's disease patient, who carried the TPMT *3C heterozygous mutant, complained of alopecia 3 days after starting (Fig. 1). After the episode, frequent clinical relapses led to infliximab therapy, which induced remission.
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