Objective: To clarify the morphological characteristics of hemifacial microsomia (HFM) by quantitative analysis of cephalometric radiographs. Design: Retrospective study of imaging data. Setting: Imaging data were obtained from the records of Sapporo Medical University Hospital. Patients: A total of 183 patients with HFM. Main Outcome Measures: We used linear and angular measurements and analyzed the middle face and lower face. Results: The ratios of the affected side to the unaffected (A/U) side of the lateral distance of the mandibular condyle, the mandibular ramus height, and the length of the body of the mandible in the HFM group were significantly lower than in the control group. The inclination of the body of the mandible was significantly larger in the side with HFM than in the unaffected side, and the extent of the mandibular ramus was significantly lower than in the unaffected side. The A/U ratios of the extent of the angle of the mandible and the inclination of the body of the mandible in the HFM group were larger than in the control group. Moreover, the length and the inclination of the body of the mandible had significant correlations with the distance of the shift of the menton. Conclusions: It is suggested that improving the hypoplasia of the length of the body of the mandible and the extent of the angle of the mandible on the affected side will lead to more effective treatment of jaw deformity in patients with HFM.

Desmoplastic fibroblastoma (DF) is a rare benign soft tissue with spindle-to-stellate-shaped fibroblasts and myofibroblasts embedded in a prominent collagenous background. DF, mainly affecting subcutaneous and muscle tissue, very rarely occurs in the oral cavity. Hitherto, only one case of DF on the tongue has been reported. Here, we report another case. A 66-year-old woman was referred to our hospital with a mass formation in the tongue. On examination, a well-circumscribed, elastic, soft tumour with normal surface mucosa, measuring 13×12 mm, was observed on the left dorsal surface of her tongue. MRI and ultrasonography confirmed the mass, and a benign tongue tumour was suspected. The tumour was surgically resected under general anaesthesia 1 month later, leading to the histopathological diagnosis of DF. She experienced an uneventful clinical recovery after surgery, with no recurrence noted for more than 1 year postoperatively.

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Cholesterol embolism is a condition in which the atheroma in a large vessel wall collapses and cholesterol crystals leak into the bloodstream, causing periphery embolization, which may be caused by catheterization or cardiovascular surgery. In this paper, we describe a case of cholesterol embolism after superselective intra-arterial chemotherapy.The patient was an 81-year-old man with right oral-floor carcinoma (T2N1M0, stage Ⅲ) . Since the patient strongly desired to preserve organ function, he underwent a total of four superselective intra-arterial chemotherapy courses by the Seldinger method combined with radiotherapy (66Gy) . Before the fifth superselective intra-arterial chemotherapy course, right toe pain, purple-red spots, and sudden renal function decrease (serum Cr level ; 1.92mg/dl, eGFR level ; 26.9ml/min) were observed, and a histopathological diagnosis of cholesterol embolism was obtained from the tissue biopsy performed at the department of dermatology. Oral administration of steroids and prostacyclin preparations improved the right toe pain ; however, renal function did not improve. After completing steroid therapy, the patient was followed up in the outpatient clinic. After 3 months, cervical lymph node resurgence was observed, and systemic drug therapy was initiated. After 10 months, the patient died of pneumonia. Reportedly, the Seldinger method causes cerebral infarction in approximately 1％ of cases. Conversely, cholesterol embolism, although extremely rare, is a disease with a poor prognosis and high probability of transitioning to hemodialysis. It is suggested that the disease should be fully considered when selecting treatment options.