Abstract. This research empirically investigates the performance of conventional rule interestingness measures and discusses their practicality for supporting KDD through human-system interaction in medical domain. We compared the evaluation results by a medical expert and those by selected measures for the rules discovered from a dataset on hepatitis. Recall, Jaccard, Kappa, CST, χ 2 -M, and Peculiarity demonstrated the highest performance, and many measures showed a complementary trend under our experimental conditions. These results indicate that some measures can predict really interesting rules at a certain level and that their combinational use will be useful.

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