The propagation of the pulse wave along the artery is relatively fast (several m/s), and a high-temporal resolution is required to measure pulse wave velocity (PWV) in a regional segment of the artery. High-frame-rate ultrasound enables the measurement of the regional PWV. In analyses of wave propagation phenomena, the direction and propagation speed are generally identified in the frequency-wavenumber space using the two-dimensional Fourier transform. However, the wavelength of the pulse wave is very long (1 m at a propagation velocity of 10 m/s and a temporal frequency of 10 Hz) compared with a typical lateral field of view of 40 mm in ultrasound imaging. Therefore, PWV cannot be identified in the frequency-wavenumber space owing to the low resolution of the two-dimensional Fourier transform. In the present study, PWV was visualized in the wavenumber domain using phases of arterial wall acceleration waveforms measured by high-frame-rate ultrasound.

In this paper, we propose an imaging method for acoustic impedance difference for puncture needle-type ultrasonography. The difference in acoustic impedance between benign and malignant tissues will provide valuable diagnostic information. In this experiment, a thin rod that has a concave polished end face was constructed using a fused quartz with a diameter of 1 mm and a focus length of 0.3 mm. An ultrasonic wave emitted from the concave end face of the rod is focused on a tissue. The difference in acoustic impedance was determined by the reflection-type interference-based acoustic impedance measurement method. We confirmed that the image shows the difference in impedance between the polyethylene (PE) plate and acrylic rod with a diameter of 3.5 mm embedded therein. The experimental results show that the method is useful for puncture needle-type ultrasonography.

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