Background: Gastro-dudenal ulcere is a global problem with a lifetime risk of development ranging from 5% to 10%. Objective: This study aims to determine the public awareness in Arar, Saudi Arabia, regarding the causes, management and prevention of gastro duodenal ulcer. Methods: A cross-sectional study was conducted in Arar city, Saudi Arabia in the period of 1 September to 30 October 2021 among the general population of Arar, Saudi Arabia. Conclusion: Almost half of the participants had knowledge about gastric or duodenal ulcers and most of them know the risk factors and possible complications. There is non-significant relationship between gastro-duodenal ulcers awareness and age, gender and educational level while a significant relationship was found between level of awareness and social status, functional status and the average monthly income of the participants.