Health professionals face increasing demands to work across discipline lines to improve patient outcomes. Learning interdisciplinary communication skills at the preprofessional level is crucial to nursing and allied health student preparation. Today’s students are technologically savvy, tired of traditional education, and often have diverse learning needs. The purpose of the pilot study was to examine the effectiveness of an interdisciplinary case study and simulation model to educate students enrolled in various health professions about asthma care and patient education. The interdisciplinary case study simulation model showed a significant advantage for both student enjoyment of the learning process and students’ confidence to coordinate care across disciplines.