This study aimed to identify the impact of digital transformation of human resources on achieving the organizational strategic sustainability through the conscious leadership as a mediating variable. This study adopted the descriptive analytical method to achieve its objective. The necessary data were collected by using a list that included several paragraphs related to the study’s variables. The annual reports of the study’s sample of three Jordanian Islamic banks were reviewed. The data of the study covered for the period 2017-2020. Results of the study showed a presence of a statistical significant impact of the digital transformation of human resources on achieving the organizational strategic sustainability in the Jordanian Islamic banks. It also indicated a statistical significant impact of the digital transformation of the human resources on the organizational strategic sustainability through mediating the conscious leadership in the Jordanian Islamic banks. The study recommends paying more attention to the digital transformation of human resources in the Islamic banks and enhancing the values of the conscious leadership and including them within the strategic plans of the banks.