This study investigated the effects of multiple blended binders on the properties and performance of concrete pavement. Mineral admixtures, namely, silica fume, metakaolin, and rice husk ash, are used to replace ordinary Portland cement at replacement levels of 0% (control mix), 5%, 10%, and 15% by mass-to-mass basis. The performance of the multiple binders on the concrete pavement properties was evaluated based on compressive strength, strength reduction, and strength activity index. Results showed that the mineral admixtures can be satisfactorily used as cement replacement materials to increase the properties of pavement concrete. Moreover, concrete pavements with 5% and 10% replacement levels exhibited excellent performance with good strength.