Background: Antibiotic stewardship is the optimum selection of antimicrobial therapy that results in the best clinical outcome for the management/ prevention of infection, with slight toxicity and minimal influence on subsequent resistance. The aim of the study was to assess the effect of an educational program on nurses' performance regarding antibiotic stewardship among high-risk neonates. Design: A quasi-experimental (pre & post-test) design used. Settings: This study was performed at Neonatal Intensive Care Units and Neonatal Surgical Intensive Care Unit of Benha Specialized Pediatric Hospital in Benha city. Sample: A purposive sample of 80 nurses and a purposive sample of 74 high-risk neonates at the previously mentioned settings. Tools of data collection: Four data collection tools were utilized, a structured interviewing questionnaire, nurses' practices observational checklists, nurses' attitudes sheet, and High-risk Neonates' Medical Record. Results:The current study demonstrated that most studied nurses (88.8%, 83.8% respectively) had a satisfactory level of knowledge and proficient level of practices after applying the educational program as compared to (8.8%, 17.5% respectively) before implementation. Conclusion: Based on the findings of the current study, studied-nurses had a satisfactory level of understanding, attitudes, and proficient level of practices after implementation of the educational program as compared to pre-program implementation with a statistically important improvement. Recommendations: The study suggest the application of traditional and online in-service training in NICUs for nurses with consistent revising of their knowledge and practices concerning antibiotic stewardship program for high-risk neonates in all NICUs.

Background: Cushing syndrome (CS) is a multisystem disease caused by long-term exposure to high levels of glucocorticoids. Slow development, weight gain, truncal obesity, facial plethora, and hypertension are all characteristics. Aim: This research aimed to see how a self-learning program affected nurses' productivity when caring for children with Cushing syndrome. A quasi experimental approach has been utilized to assess the influence of a self-learning course on nurses' effectiveness in caring for children with Cushing syndrome. Settings: This study was conducted in the pediatric and hereditary units of a pediatric hospital associated with Ain Shams University. Sample: A practical selection of all nurses working in pediatric and hereditary units (80 bedside male and female nurses) from the starting of January 2021 to the end of June 2021. Tools of data collection: To obtain findings for this research, two techniques were used: a standardized interviewing survey form, as well as observational evaluations of nursing care provided to children with CS. Results: Nurses' understanding of CS was insufficient during the pre-module phase, although there is a statistically considerable variation between pre and post learning module deployment. Nurses' awareness, practice, and before and post module implementation all have a beneficial relationship. Conclusion The nurses evaluated who care for children suffering Cushing syndrome had an inadequate level of knowledge regarding Cushing syndrome, its long-term implications, and long-term continuous therapy. Also, after implementing the module, the studied nurses had a competence practice level in caring for children with Cushing syndrome. Recommendation: Enhancing nurses' understanding for value of self-learning modules on the growth of their technical skills as well as the quality of care delivered to children with CS through in-service training activities in various health care institutions.