Polysplenia syndrome is an uncommon condition associating several splenic nodules (sometimes polylobed spleen and cases of normal spleen have been described) with a number of malformations that appear between the fourth and sixth week of embryonic development. Although it has been suggested that genetic, teratogenic, and embryogenic factors may be at fault, the exact etiology remains unclear. Clinically, it is generally asymptomatic or mildly symptomatic. The authors report the case of an 11-months-old infant from a poorly monitored pregnancy. He was admitted to the emergency room for respiratory discomfort in a context of apyrexia. A thoraco-abdominal CT scanner revealed a polysplenia syndrome.

Introduction: Neuroblastoma is the third most common malignancy in pediatrics, subcutaneous metastases of antenatal neuroblastoma are described in the literature and they represent 1% of secondary localizations of neuroblastoma. Case Report: We report the case of a 12-month-old male infant with an antenatal neuroblastoma of the left adrenal gland revealed by inguino-scrotal and forearm subcutaneous nodules whose anatomopathological study was in favor of cutaneous metastases of a neuroblastoma. Conclusion: Neuroblastoma is a very frequent embryonic tumor in pediatrics, subcutaneous metastases are often revealing of antenatal neuroblastoma, the diagnosis of certainty is essentially based on anatomopathological study.

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