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CONTEXTMusculoskeletal tumours are diverse in their gross and morphological features and range in their biologic potential from the innocuous to the rapidly fatal. This diversity makes it critical to accurately diagnose and stage tumours and treat them appropriately. AIMSThe present study was undertaken to evaluate musculoskeletal tumours by Magnetic Resonance Imaging (MRI) and to correlate findings of MRI with histopathological/surgical findings. SETTINGS AND DESIGN/METHODS AND MATERIALThe present study includes 50 patients of musculoskeletal tumours suspected clinically and/or on plain radiography. All patients included in the study were subjected to detailed clinical history and physical examination in order to determine the nature, site of origin and extent of musculoskeletal mass. Plain roentgenogram in anteroposterior and lateral views, MRI examinations with 1.5 T units on GE HDXT 1.5 Tesla 16 channel MRI were done. Sequences used were conventional. Proton density fat suppression (axial/coronal/sagittal), T1WTSE (axial/coronal) [TR = 600 msec, TE = 15 msec], T2WTSE (axial/coronal) [TR = 3780 msec, TE = 100 msec], Merge/Gradient [TR = 500 msec; TE = 18 msec] in multiple planes. Intravenous contrast (post contrast T1 FS in all 3 planes) was used in all patients. The findings of MR were correlated with histopathological/surgical findings.