Objectives
Head and neck cancer (HNC) patients are at high risk for late occurring radiation‐related morbidity and recurrence, necessitating close long‐term medical surveillance. This study identified factors associated with becoming lost to follow‐up (LTFU) at a comprehensive cancer center.
Materials and Methods
Patients were drawn from survivors who received radiation for HNC at a single institution between 2001 and 2018. LTFU was defined as living patients without a clinical encounter within 2 years of the data query.
Results
In total, 537 patients met the inclusion criteria and 57 (10.6%) were identified as LTFU. Individual comparisons identified time since completing radiation, non‐White race and being unmarried as associated with LTFU. Multiple regression identified time since treatment and being unmarried as factors associated with LTFU. A decision tree correctly sorted 89.4% using time, distance, and marital status.
Conclusion
Time since radiation, distance to clinic, and being unmarried were factors associated with becoming LTFU.
The degree of hippocampal dentation, a morphologic feature of the inferior surface of the human hippocampus, has been positively associated with episodic memory performance in healthy adults. This study examined hippocampal dentation in healthy children and adolescents. The Cincinnati MR Imaging of NeuroDevelopment (C-MIND) dataset was used to examine the relationship between age and hippocampal dentation in 90 healthy children, age < 1 to 18 years old, using T1-weighted MPRAGE scans. Hippocampal dentation was assessed by counting the number of dentes for the left and right hippocampi. Participants had slightly more left than right hippocampal dentes, on average. Dentation did not differ significantly between males and females. Correlational analyses revealed that the numbers of left, right, and total dentes were positively associated with age in this sample. Interestingly, these data highlight the wide variability of dentation in older age groups. While younger children tended to have absent or few dentes, a range of dentation was present in older children and adolescents (ranging from absent to numerous, bilaterally). This is consistent with previous research in a healthy adult cohort, where a range of dentation was also observed. This study is the first to examine hippocampal dentation in children.
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