BackgroundSuboptimal treatment adherence remains a barrier to the control of many infectious diseases, including tuberculosis and HIV/AIDS, which contribute significantly to the global disease burden. However, few of the many interventions developed to address this issue explicitly draw on theories of health behaviour. Such theories could contribute to the design of more effective interventions to promote treatment adherence and to improving assessments of the transferability of these interventions across different health issues and settings.MethodsThis paper reviews behaviour change theories applicable to long-term treatment adherence; assesses the evidence for their effectiveness in predicting behaviour change; and examines the implications of these findings for developing strategies to improve TB and HIV/AIDS medication adherence. We searched a number of electronic databases for theories of behaviour change. Eleven theories were examined.ResultsLittle empirical evidence was located on the effectiveness of these theories in promoting adherence. However, several models have the potential to both improve understanding of adherence behaviours and contribute to the design of more effective interventions to promote adherence to TB and HIV/AIDS medication.ConclusionFurther research and analysis is needed urgently to determine which models might best improve adherence to long-term treatment regimens.

While migration in South Africa has been studied on a broad canvas, there have been few accounts of children's migration and the effects on living conditions and wellbeing.

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Urban populations are growing rapidly in developing countries. As a result, challenges to the well-being of adolescents are increasing in priority. This paper describes the material and social living conditions of 5,367 young adolescents, in Johannesburg-Soweto, South Africa in [2002][2003]. The majority of children in South Africa's urban hub have adequate access to basic services. However, social conditions are a key concern-lack of financial support by parents; defaulting caregiver roles to grandparents; minimal or no contact with fathers; and poor school performance. Weakened levels of family support in urban environments may negatively impact on adolescent development. In the long term, family systems as well as other social networks and institutions need to be strengthened to improve adolescent outcomes.

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