The first Pd-catalyzed multicomponent reaction of aryl iodides, alkenyl bromides, and strained alkenes has been developed, which allowed us to synthesize a variety of multisubsituted olefins in yields of 45-96% with excellent stereoselectivity. The configuration of the product was controlled by the configuration of the alkenyl bromides. Moreover, this practical methodology employing readily available substrates was found to be tolerant to a wide range of functional groups. Fifty six examples of highly stereoselective tri- or tetrasubstituted olefins have been successfully synthesized via this methodology. Most of the synthesized tetrasubstituted olefins are good aggregation-induced emission (AIE) luminogens.

Quantitative Z → E isomerization was catalyzed by trace mild acids to offer molecular switches orthogonally controllable by acid and light.

A new series of octahedral rhodium(III) complexes 1–8 of the type [(Ln)2Rh(dppz)]Cl (n = 1–6) and [(Ln)2Rh(dppz)](PF6) {n = 1, 7, 8; L = 2‐phenylpyridine, with different modifications, as the C,N‐chelating ligand; and dppz = dipyrido[3,2‐a:2′,3′‐c]phenazine} have been synthesized and fully characterized. The photophysical properties of the complexes have been investigated. The single‐crystal X‐ray diffraction structures of five complexes – [(L1)2Rh(dppz)](PF6), [(L2)2Rh(dppz)]Cl, [(L3)2Rh(dppz)](PF6), [(L4)2Rh(dppz)](PF6), and [(L8)2Rh(dppz)](PF6) – have confirmed the anticipated structure and have revealed the effect of substitution on the structure of the complex, which has been reasonably explained through experimental electrochemical characterization. The interaction of complexes 1–8 with calf thymus DNA (CT DNA) has been verified by the fluorescent detection of ethidium bromide (EB) displacement studies. The result clearly suggests that the DNA‐binding abilities of these Rh complexes are not only influenced by the DNA‐intercalator dppz, but are also highly influenced by the electronic and steric properties of the C,N‐chelating ligands.

The design and development of specific recognition and sensing systems for biologically important anionic species has received growing attention in recent years, as they play significant roles in biology, pharmacy, and environmental sciences. Herein, a new supramolecular sensing probe L1 was developed for highly selective differentiation of nucleotides. L1 displayed extremely marked absorption and emission differentiation upon binding with nucleotide homologs of AMP, ADP, and ATP, due to the divergent spatial orientations of guests upon binding, which allowed for a naked-eye colorimetric differentiation for nucleotides. A differentiating mechanism was unambiguously rationalized by using various spectroscopic studies and theoretical calculations. Furthermore, we successfully demonstrated that L1 can be applied to the real-time monitoring of the enzyme-catalyzed phosphorylation/dephosphorylation processes and thus demonstrated an unprecedented visualizable strategy for selectively differentiating the structurally similar nucleotides and real-time monitoring of biological processes via fluorescent and colorimetric changes.

The Front Cover shows the interaction of Rh complexes with DNA in a design inspired by the Chinese classical novel “Romance of the Three Kingdoms”. According to the story, three heroes, Liu Bei, Guan Yu, and Zhang Fei, fought together against Lv Bu in the Eastern Han Dynasty. Eight new octahedral rhodium complexes have been reported in our paper. Three single‐crystal structures, representing the three heroes, are displayed in the cover picture, while DNA represents Lv Bu. We thank Zonghan Yu, who contributed to the idea of the cover with Chinese elements. More information can be found in the https://doi.org/10.1002/ejic.201700700 For more on the story behind the cover research, see the https://doi.org/10.1002/ejic.201700961.