The impact of episodic stress is accentuated in the midst of chronic interpersonal stress and diminished in its absence. Simultaneous exposure to episodic and chronic stress may create wear and tear on the body, whereas exposure to episodic stress in the context of a supportive environment may toughen the body, protecting it against subsequent stressors.

Depression is related to increased morbidity and mortality from coronary heart disease (CHD), but the underlying mechanisms are unclear. One possibility is that depressive symptoms influence CHD pathogenesis by fostering endothelial dysfunction. To evaluate this possibility, we studied one hundred and two adolescent women with no known or suspected major health problems. Depressive symptoms were assessed using the Beck Depression Inventory (BDI) and endothelial function with a noninvasive beat-to-beat plethysmographic recording of the finger arterial pulse-wave amplitude (PWA) before and after occlusion of the brachial artery. Regression analysis revealed a significant inverse relationship between depressive symptoms and endothelial function. This persisted after controlling for age, ethnicity, health practices and waist circumference. Depression explained 4-6% of the variance in endothelial function above and beyond the effects of covariates. Most patients in our sample had subclinical depressive symptoms, suggesting that even mild affective difficulties are capable of negatively influencing endothelial function in otherwise healthy youngsters.

Research shows that poor social ties increase risks of morbidity and mortality from cardiovascular disease (CVD). However, little is known about the nature of everyday social encounters that give rise to this association, or when in the course of development they begin to shape disease-relevant biological processes. In this study, 122 adolescent females recorded the qualities of their everyday social interactions using electronic diaries. At the same time we measured components of the metabolic syndrome, a precursor to CVD that includes central adiposity, high blood pressure, insulin resistance, and lipid dysregulation. Metabolic symptoms were reassessed 12 and 24 months later. Hierarchical linear modeling revealed an association between negative social interactions and metabolic symptom trajectories. To the extent that participants had more intense negative social encounters in daily life, they showed increasing scores on a composite indicator of metabolic risk over two years. This association was independent of a variety of potential confounders, and persisted when symptoms of depression and broader personality traits were controlled. There was no association between positive social encounters and metabolic risk trajectories. These findings suggest that even in otherwise healthy adolescents, abrasive social encounters may accelerate the progression of CVD’s early stages.

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In the midst of the freezing winter of 1978 and 1979, strikes erupted across Britain. In what became infamously known as the “Winter of Discontent,” workers struck against the Labour Government's attempts to curtail wage increases. The defeat of this “incomes policy” and Labour's subsequent electoral defeat ushered in an era of unprecedented political, economic, and social change for Britain. Conservative victory, under the leadership of Margaret Thatcher, not only seemed to signal the dissolution of “traditional” working-class ties to the Labour Party, it also suggested that British working-class politics might finally be on its last leg. Furthermore, a potent social myth developed around the Winter of Discontent, one where “bloody-minded” workers brought down a sympathetic government and “invited” the ravages of Thatcherism upon the British labor movement.Absent from these various narratives are the experiences of rank-and-file activists, in particular, the growing number of female trade unionists active in these strikes. This article examines the experiences of a group of women trade unionists from the National Union of Public Employees (NUPE) who participated in the strikes of the Winter of Discontent. Based on oral histories and corresponding archival material, it argues that the Winter of Discontent provided a crucial “rite of passage” for these women, one which exposed them to an unprecedented level of involvement in grassroots labor activism and leadership. Thereafter, these working-class women began to make significant inroads into NUPE and the Labour Party, which helped to make working women's issues more central to the British labor movement for decades to come. Therefore, rather than being the death knell of British working-class politics, this study of women involved in the Winter of Discontent strikes reveals that while one form of working-class politics was in decline, a reconfigured one was in the process of being born.